Identity
HGNC
LOCATION
1q32.2
LOCUSID
ALIAS
C3DR,CD21,CR,CVID7,SLEB9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1380
MIM: 120650
HGNC: 2336
Ensembl: ENSG00000117322
Variants:
dbSNP: 1380
ClinVar: 1380
TCGA: ENSG00000117322
COSMIC: CR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117322 | ENST00000367057 | P20023 |
| ENSG00000117322 | ENST00000367058 | P20023 |
| ENSG00000117322 | ENST00000367059 | Q5SR47 |
| ENSG00000117322 | ENST00000640301 | A0A1W2PPV2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38287771 | 2024 | Oral lupus erythematosus: Immunohistochemical evaluation of CD1a, CD21, CD123, and langerin expression in dendritic cells. | 0 |
| 38287771 | 2024 | Oral lupus erythematosus: Immunohistochemical evaluation of CD1a, CD21, CD123, and langerin expression in dendritic cells. | 0 |
| 36971659 | 2023 | Identification and Characterization of chCR2, a Protein That Binds Chicken Complement Component 3d. | 1 |
| 37833411 | 2023 | Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity. | 0 |
| 36971659 | 2023 | Identification and Characterization of chCR2, a Protein That Binds Chicken Complement Component 3d. | 1 |
| 37833411 | 2023 | Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity. | 0 |
| 33868238 | 2021 | Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells. | 17 |
| 34623902 | 2021 | The expansion of human T-bet(high)CD21(low) B cells is T cell dependent. | 47 |
| 33868238 | 2021 | Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells. | 17 |
| 34623902 | 2021 | The expansion of human T-bet(high)CD21(low) B cells is T cell dependent. | 47 |
| 31634193 | 2020 | Association of complement C3d receptor 2 genotypes with the acquisition of HIV infection in a trial of recombinant glycoprotein 120 vaccine. | 8 |
| 32238579 | 2020 | CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells. | 25 |
| 32552036 | 2020 | Association Between Genetic Polymorphisms of CR2 Gene and the Risk of Steroid-Induced Osteonecrosis of the Femoral Head in the Chinese Han Male Population. | 4 |
| 32907998 | 2020 | Naive- and Memory-like CD21(low) B Cell Subsets Share Core Phenotypic and Signaling Characteristics in Systemic Autoimmune Disorders. | 21 |
| 33129017 | 2020 | Notch signaling induces a transcriptionally permissive state at the Complement C3d Receptor 2 (CR2) promoter in a pre-B cell model. | 1 |
Citation
Dessen P
CR2 (complement C3d receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-08-01
Online version: http://atlasgeneticsoncology.org/gene/51049/cr2
