Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 493829
MIM: 613288
HGNC: 32671
Ensembl: ENSG00000177238
Variants:
dbSNP: 493829
ClinVar: 493829
TCGA: ENSG00000177238
COSMIC: TRIM72
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177238 | ENST00000322122 | Q6ZMU5 |
| ENSG00000177238 | ENST00000613872 | Q6ZMU5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Smooth Muscle Contraction | REACTOME | R-HSA-445355 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36814155 | 2023 | Tripartite motif 72 inhibits apoptosis and mitochondrial dysfunction in neural stem cells induced by anesthetic sevoflurane by activating PI3K/AKT pathway. | 0 |
| 37169128 | 2023 | MG53 ameliorates nerve injury induced neuropathic pain through the regulation of Nrf2/HO-1 signaling in rats. | 0 |
| 36814155 | 2023 | Tripartite motif 72 inhibits apoptosis and mitochondrial dysfunction in neural stem cells induced by anesthetic sevoflurane by activating PI3K/AKT pathway. | 0 |
| 37169128 | 2023 | MG53 ameliorates nerve injury induced neuropathic pain through the regulation of Nrf2/HO-1 signaling in rats. | 0 |
| 34958003 | 2022 | Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment. | 4 |
| 35324524 | 2022 | TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA. | 6 |
| 35438597 | 2022 | MG53 represses high glucose-induced inflammation and angiogenesis in human retinal endothelial cells by repressing the EGR1/STAT3 axis. | 5 |
| 36053137 | 2022 | Cryo-EM structure of human MG53 homodimer. | 2 |
| 34958003 | 2022 | Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment. | 4 |
| 35324524 | 2022 | TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA. | 6 |
| 35438597 | 2022 | MG53 represses high glucose-induced inflammation and angiogenesis in human retinal endothelial cells by repressing the EGR1/STAT3 axis. | 5 |
| 36053137 | 2022 | Cryo-EM structure of human MG53 homodimer. | 2 |
| 33482040 | 2021 | Targeting TRIM Proteins: A Quest towards Drugging an Emerging Protein Class. | 17 |
| 33566837 | 2021 | MG53 is not a critical regulator of insulin signaling pathway in skeletal muscle. | 10 |
| 33744959 | 2021 | Functional and Adaptive Significance of Promoter Mutations That Affect Divergent Myocardial Expressions of TRIM72 in Primates. | 1 |
Citation
Dessen P
TRIM72 (tripartite motif containing 72)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51078/trim72
