CDH22 (cadherin 22)

2009-09-01  

Identity

HGNC
CDH22
LOCATION
20q13.12
LOCUSID
64405
ALIAS
C20orf25,dJ998H6.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64405
MIM: 609920
HGNC: 13251
Ensembl: ENSG00000149654

Variants:

dbSNP: 64405
ClinVar: 64405
TCGA: ENSG00000149654
COSMIC: CDH22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149654ENST00000537909Q9UJ99

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
289912292018Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.18
289912292018Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion.18
281493352017CDH22 hypermethylation is an independent prognostic biomarker in breast cancer.5
281493352017CDH22 hypermethylation is an independent prognostic biomarker in breast cancer.5
206503122010Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.22
206503122010Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.22
194400362009PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly.18
195466062009Over-expression of CDH22 is associated with tumor progression in colorectal cancer.10
194400362009PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly.18
195466062009Over-expression of CDH22 is associated with tumor progression in colorectal cancer.10
186029832008Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.20
186029832008Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.20
86267161996Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin.17
86267161996Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin.17

Citation

Dessen P

CDH22 (cadherin 22)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51088