LSAMP (limbic system associated membrane protein)

2009-09-01  

Identity

HGNC
LSAMP
LOCATION
3q13.31
LOCUSID
4045
ALIAS
IGLON3,LAMP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4045
MIM: 603241
HGNC: 6705
Ensembl: ENSG00000185565

Variants:

dbSNP: 4045
ClinVar: 4045
TCGA: ENSG00000185565
COSMIC: LSAMP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185565ENST00000333617H3BLU2
ENSG00000185565ENST00000474851C9J5G3
ENSG00000185565ENST00000490035Q13449
ENSG00000185565ENST00000539563F5H5G1

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447199Bipolar DisorderDiseaseLiterature, MultilinkAnnotationassociated24718920

References

Pubmed IDYearTitleCitations
366017482023Identification of recurrent 3q13.31 chromosomal rearrangement indicates LSAMP as a tumor suppressor gene in neuroblastoma.3
366017482023Identification of recurrent 3q13.31 chromosomal rearrangement indicates LSAMP as a tumor suppressor gene in neuroblastoma.3
323836162020Limbic System Associated Membrane Protein Mutation in an Iranian Family Diagnosed with Ménière's Disease.6
323836162020Limbic System Associated Membrane Protein Mutation in an Iranian Family Diagnosed with Ménière's Disease.6
276933472017Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.69
276933472017Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.69
268442742015A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.48
268442742015A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men.48
244916862014Associations between polymorphisms of LSAMP gene and schizophrenia.12
248852972014Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model.16
244916862014Associations between polymorphisms of LSAMP gene and schizophrenia.12
248852972014Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model.16
228927172012Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder.23
228927172012Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder.23
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

LSAMP (limbic system associated membrane protein)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51101/gene-fusions-explorer/case-report-explorer/js/lib/zoomerang.js