Identity
HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
HEP27,SDR25C1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10202
MIM: 615194
HGNC: 18349
Ensembl: ENSG00000100867
Variants:
dbSNP: 10202
ClinVar: 10202
TCGA: ENSG00000100867
COSMIC: DHRS2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37060745 | 2023 | Regulatory mechanism of DHRS2-modified human umbilical cord mesenchymal stem cells-derived exosomes in prostate cancer cell proliferation and apoptosis. | 1 |
| 37119764 | 2023 | Epigenetic regulation of DHRS2 by SUV420H2 inhibits cell apoptosis in renal cell carcinoma. | 1 |
| 37060745 | 2023 | Regulatory mechanism of DHRS2-modified human umbilical cord mesenchymal stem cells-derived exosomes in prostate cancer cell proliferation and apoptosis. | 1 |
| 37119764 | 2023 | Epigenetic regulation of DHRS2 by SUV420H2 inhibits cell apoptosis in renal cell carcinoma. | 1 |
| 36192391 | 2022 | DHRS2 inhibits cell growth and metastasis in ovarian cancer by downregulation of CHKα to disrupt choline metabolism. | 4 |
| 36192391 | 2022 | DHRS2 inhibits cell growth and metastasis in ovarian cancer by downregulation of CHKα to disrupt choline metabolism. | 4 |
| 31423895 | 2020 | Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer. | 8 |
| 32586085 | 2020 | LEF1 Induces DHRS2 Gene Expression in Human Acute Leukemia Jurkat T-Cells. | 1 |
| 31423895 | 2020 | Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer. | 8 |
| 32586085 | 2020 | LEF1 Induces DHRS2 Gene Expression in Human Acute Leukemia Jurkat T-Cells. | 1 |
| 30460772 | 2019 | Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors. | 15 |
| 30535463 | 2019 | Molecular pathogenesis of esophageal squamous cell carcinoma: Identification of the antitumor effects of miR‑145‑3p on gene regulation. | 18 |
| 31291971 | 2019 | DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma. | 16 |
| 31436301 | 2019 | Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression. | 3 |
| 30460772 | 2019 | Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors. | 15 |
Citation
Dessen P
DHRS2 (dehydrogenase/reductase 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51136/dhrs2
