TADA3 (transcriptional adaptor 3)

2009-10-01  

Identity

HGNC
LOCATION
3p25.3
LOCUSID
ALIAS
ADA3,NGG1,STAF54,TADA3L,hADA3
FUSION GENES

Other Information

Locus ID:

NCBI: 10474
MIM: 602945
HGNC: 19422
Ensembl: ENSG00000171148

Variants:

dbSNP: 10474
ClinVar: 10474
TCGA: ENSG00000171148
COSMIC: TADA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171148ENST00000301964O75528
ENSG00000171148ENST00000343450O75528
ENSG00000171148ENST00000343450A0A024R2D7
ENSG00000171148ENST00000439043C9JMS0
ENSG00000171148ENST00000440161O75528

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847
DeubiquitinationREACTOMER-HSA-5688426
Ub-specific processing proteasesREACTOMER-HSA-5689880

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370059552023Transcriptional adaptor 3 influences the proliferative and invasive phenotypes of non-small cell lung cancer cells via regulating EMT.0
370059552023Transcriptional adaptor 3 influences the proliferative and invasive phenotypes of non-small cell lung cancer cells via regulating EMT.0
309543472019Overexpression of Alteration/Deficiency in Activation 3 correlates with poor prognosis in non-small cell lung cancer.0
309543472019Overexpression of Alteration/Deficiency in Activation 3 correlates with poor prognosis in non-small cell lung cancer.0
296701082018Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.11
296701082018Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer.11
280603822017Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization.24
287592942017Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.9
280603822017Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization.24
287592942017Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.9
274028652016Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation.6
276053782016Tale of a multifaceted co-activator, hADA3: from embryogenesis to cancer and beyond.2
278523272016ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC.6
274028652016Acetylation of Mammalian ADA3 Is Required for Its Functional Roles in Histone Acetylation and Cell Proliferation.6
276053782016Tale of a multifaceted co-activator, hADA3: from embryogenesis to cancer and beyond.2

Citation

Dessen P

TADA3 (transcriptional adaptor 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-10-01

Online version: http://atlasgeneticsoncology.org/gene/51166/tada3