PGLYRP1 (peptidoglycan recognition protein 1)

2009-11-01  

Identity

HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
PGLYRP,PGRP,PGRP-S,PGRPS,TAG7,TNFSF3L

Other Information

Locus ID:

NCBI: 8993
MIM: 604963
HGNC: 8904
Ensembl: ENSG00000008438

Variants:

dbSNP: 8993
ClinVar: 8993
TCGA: ENSG00000008438
COSMIC: PGLYRP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008438ENST00000008938O75594

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383939472024The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes.1
383939472024The microglial innate immune protein PGLYRP1 mediates neuroinflammation and consequent behavioral changes.1
375299852023Value of gingival crevicular fluid TREM-1, PGLYRP1, and IL-1β levels during menopause.0
375299852023Value of gingival crevicular fluid TREM-1, PGLYRP1, and IL-1β levels during menopause.0
353442082022Association of peptidoglycan recognition protein 1 to post-myocardial infarction and periodontal inflammation: A subgroup report from the PAROKRANK (Periodontal Disease and the Relation to Myocardial Infarction) study.2
353671942022TNF upregulates peptidoglycan recognition protein 1 in esophageal cancer cells to clear the path to its signaling: Making the "enemy" a friend.1
356285622022N-Terminal Peptide of PGLYRP1/Tag7 Is a Novel Ligand for TREM-1 Receptor.3
353442082022Association of peptidoglycan recognition protein 1 to post-myocardial infarction and periodontal inflammation: A subgroup report from the PAROKRANK (Periodontal Disease and the Relation to Myocardial Infarction) study.2
353671942022TNF upregulates peptidoglycan recognition protein 1 in esophageal cancer cells to clear the path to its signaling: Making the "enemy" a friend.1
356285622022N-Terminal Peptide of PGLYRP1/Tag7 Is a Novel Ligand for TREM-1 Receptor.3
337607992021Circulating PGLYRP1 Levels as a Potential Biomarker for Coronary Artery Disease and Heart Failure.6
337607992021Circulating PGLYRP1 Levels as a Potential Biomarker for Coronary Artery Disease and Heart Failure.6
314446932020The modulation of the TREM-1/PGLYRP1/MMP-8 axis in peri-implant diseases.5
315874602020The effect of smoking on gingival crevicular fluid peptidoglycan recognition protein-1 level following initial periodontal therapy in chronic periodontitis.1
318608042020Regulation of Salivary Peptidoglycan Recognition Protein 1 in Adolescents.5

Citation

Dessen P

PGLYRP1 (peptidoglycan recognition protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51175/pglyrp1