MTUS2 (microtubule associated scaffold protein 2)

2009-11-01 Affiliation

Identity

HGNC

MTUS2

LOCATION

13q12.3

LOCUSID

23281

ALIAS

CAZIP,ICIS,KIAA0774,TIP150

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 23281
HGNC: 20595
Ensembl: ENSG00000132938

Variants:

dbSNP: 23281
ClinVar: 23281
TCGA: ENSG00000132938
COSMIC: MTUS2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000132938	ENST00000380808	Q5JR59
ENSG00000132938	ENST00000542829	Q5JR59
ENSG00000132938	ENST00000612955	Q5JR59

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38380866	2024	Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.	1
38380866	2024	Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.	1
27451391	2016	The Microtubule Plus End Tracking Protein TIP150 Interacts with Cortactin to Steer Directional Cell Migration.	16
27451391	2016	The Microtubule Plus End Tracking Protein TIP150 Interacts with Cortactin to Steer Directional Cell Migration.	16
24847103	2014	Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction.	27
24847103	2014	Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction.	27
23595990	2013	Regulation of a dynamic interaction between two microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis.	20
23595990	2013	Regulation of a dynamic interaction between two microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis.	20
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
19543227	2009	TIP150 interacts with and targets MCAK at the microtubule plus ends.	42
19806667	2009	CAZIP, a novel protein expressed in the developing heart and nervous system.	6
19543227	2009	TIP150 interacts with and targets MCAK at the microtubule plus ends.	42
19806667	2009	CAZIP, a novel protein expressed in the developing heart and nervous system.	6

Citation

Dessen P

MTUS2 (microtubule associated scaffold protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51207