MR1 (major histocompatibility complex, class I-related)

2009-11-01  

Identity

HGNC
MR1
LOCATION
1q25.3
LOCUSID
3140
ALIAS
HLALS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3140
MIM: 600764
HGNC: 4975
Ensembl: ENSG00000153029

Variants:

dbSNP: 3140
ClinVar: 3140
TCGA: ENSG00000153029
COSMIC: MR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153029ENST00000282990Q95460
ENSG00000153029ENST00000367579Q95460
ENSG00000153029ENST00000367580Q95460
ENSG00000153029ENST00000434571Q95460
ENSG00000153029ENST00000614012Q95460
ENSG00000153029ENST00000617803Q95460

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
377732722024MR1 antigen presentation to MAIT cells and other MR1-restricted T cells.4
381579452024The MR1/MAIT cell axis in CNS diseases.1
377732722024MR1 antigen presentation to MAIT cells and other MR1-restricted T cells.4
381579452024The MR1/MAIT cell axis in CNS diseases.1
366309192023Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing.25
368451062023Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation.4
369449692023Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.5
380170212023Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients.0
366309192023Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing.25
368451062023Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation.4
369449692023Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.5
380170212023Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients.0
349684632022The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.3
361294342022A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.6
349684632022The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.3

Citation

Dessen P

MR1 (major histocompatibility complex, class I-related)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51228