OXGR1 (oxoglutarate receptor 1)

2010-01-01  

Identity

HGNC
OXGR1
LOCATION
13q32.1
LOCUSID
27199
ALIAS
GPR80,GPR99,P2RY15,P2Y15,aKGR

Other Information

Locus ID:

NCBI: 27199
MIM: 606922
HGNC: 4531
Ensembl: ENSG00000165621

Variants:

dbSNP: 27199
ClinVar: 27199
TCGA: ENSG00000165621
COSMIC: OXGR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165621ENST00000298440Q96P68
ENSG00000165621ENST00000298440B2R986
ENSG00000165621ENST00000541038F5H6U5
ENSG00000165621ENST00000541518F5H3P1
ENSG00000165621ENST00000543457Q96P68
ENSG00000165621ENST00000543457B2R986

Expression (GTEx)

0
1
2
3
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
365714632023OXGR1 is a candidate disease gene for human calcium oxalate nephrolithiasis.0
365714632023OXGR1 is a candidate disease gene for human calcium oxalate nephrolithiasis.0
331213112021Changes in expression of orphan receptors GPR99 and GPR107 during the development and establishment of hypertension in spontaneously hypertensive rats.3
331213112021Changes in expression of orphan receptors GPR99 and GPR107 during the development and establishment of hypertension in spontaneously hypertensive rats.3
321049232020Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation.26
321049232020Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation.26
273241802017Expression and localization of GPR99 in human nasal mucosa.1
273241802017Expression and localization of GPR99 in human nasal mucosa.1
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
197606082009Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma.14
197606082009Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma.14
150015732004Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine.26
150015732004Identification and characterization of a cell-surface receptor, P2Y15, for AMP and adenosine.26

Citation

Dessen P

OXGR1 (oxoglutarate receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51279