ELOVL7 (ELOVL fatty acid elongase 7)

2010-01-01  

Identity

HGNC
ELOVL7
LOCATION
5q12.1
LOCUSID
79993
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79993
MIM: 614451
HGNC: 26292
Ensembl: ENSG00000164181

Variants:

dbSNP: 79993
ClinVar: 79993
TCGA: ENSG00000164181
COSMIC: ELOVL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164181ENST00000425382A1L3X0
ENSG00000164181ENST00000504455D6RE10
ENSG00000164181ENST00000505959D6RHD0
ENSG00000164181ENST00000507047D6RBM2
ENSG00000164181ENST00000508821A1L3X0
ENSG00000164181ENST00000511799D6RBM2
ENSG00000164181ENST00000514809D6RBR5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Fatty acid elongationKEGGhsa00062
Fatty acid biosynthesis, elongation, endoplasmic reticulumKEGGhsa_M00415
Fatty acid biosynthesis, elongation, endoplasmic reticulumKEGGM00415
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105
Synthesis of very long-chain fatty acyl-CoAsREACTOMER-HSA-75876

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369304942023ELOVL fatty acid elongase 7 (ELOVL7), upregulated by Mdr2-knockout, predicts advanced liver fibrosis in patients with chronic hepatitis B.1
369304942023ELOVL fatty acid elongase 7 (ELOVL7), upregulated by Mdr2-knockout, predicts advanced liver fibrosis in patients with chronic hepatitis B.1
336009082021Investigating ELOVL7 coding variants in multiple system atrophy.2
341174792021The structural basis of fatty acid elongation by the ELOVL elongases.31
336009082021Investigating ELOVL7 coding variants in multiple system atrophy.2
341174792021The structural basis of fatty acid elongation by the ELOVL elongases.31
279287002017Gene expression signatures for phlegm-dampness constitution of Chinese medicine.8
279287002017Gene expression signatures for phlegm-dampness constitution of Chinese medicine.8
257328272015Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication.45
257328272015Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication.45
219590402011Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.48
219590402011Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.48
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
198260532009Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.91

Citation

Dessen P

ELOVL7 (ELOVL fatty acid elongase 7)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51307/js/lib/deep-insight-explorer/img/logo-atlas-4.svg