Identity
HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
HSPC046,LAB,NTAL,WBSCR15,WBSCR5,WSCR5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7462
MIM: 605719
HGNC: 12749
Ensembl: ENSG00000086730
Variants:
dbSNP: 7462
ClinVar: 7462
TCGA: ENSG00000086730
COSMIC: LAT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36902005 | 2023 | Expression of Non-T Cell Activation Linker (NTAL) in Jurkat Cells Negatively Regulates TCR Signaling: Potential Role in Rheumatoid Arthritis. | 0 |
| 36902005 | 2023 | Expression of Non-T Cell Activation Linker (NTAL) in Jurkat Cells Negatively Regulates TCR Signaling: Potential Role in Rheumatoid Arthritis. | 0 |
| 32587277 | 2020 | NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia. | 5 |
| 32587277 | 2020 | NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia. | 5 |
| 31060403 | 2019 | The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma. | 1 |
| 31060403 | 2019 | The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma. | 1 |
| 28815339 | 2017 | Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma. | 2 |
| 28815339 | 2017 | Expression of large neutral amino acid transporters LAT1 and LAT2 in medulloblastoma. | 2 |
| 24456692 | 2014 | The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells. | 4 |
| 24456692 | 2014 | The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells. | 4 |
| 22269118 | 2012 | The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL. | 3 |
| 23001822 | 2012 | Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity. | 11 |
| 22269118 | 2012 | The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL. | 3 |
| 23001822 | 2012 | Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity. | 11 |
| 20643813 | 2011 | LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes? | 12 |
Citation
Dessen P
LAT2 (linker for activation of T cells family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51310/lat2
