IFNK (interferon kappa)

2010-01-01  

Identity

HGNC
LOCATION
9p21.2
LOCUSID
ALIAS
IFNT1,INFE1
FUSION GENES

Other Information

Locus ID:

NCBI: 56832
MIM: 615326
HGNC: 21714
Ensembl: ENSG00000147896

Variants:

dbSNP: 56832
ClinVar: 56832
TCGA: ENSG00000147896
COSMIC: IFNK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147896ENST00000276943Q9P0W0

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
RIG-I-like receptor signaling pathwayKEGGko04622
RIG-I-like receptor signaling pathwayKEGGhsa04622

References

Pubmed IDYearTitleCitations
366942232023Identification of the prognostic value of Th1/Th2 ratio and a novel prognostic signature in basal-like breast cancer.2
369281172023Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction.4
366942232023Identification of the prognostic value of Th1/Th2 ratio and a novel prognostic signature in basal-like breast cancer.2
369281172023Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction.4
343648832022IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation.6
353580912022IFN-κ is critical for normal wound repair and is decreased in diabetic wounds.4
343648832022IFN-κ Is a Rheostat for Development of Psoriasiform Inflammation.6
353580912022IFN-κ is critical for normal wound repair and is decreased in diabetic wounds.4
316663852020Human Papillomavirus 16 E5 Inhibits Interferon Signaling and Supports Episomal Viral Maintenance.41
319559632020MDA5(+) Dermatomyositis Is Associated with Stronger Skin Type I Interferon Transcriptomic Signature with Upregulation of IFN-κ Transcript.18
323520192020Interferon Kappa Is Important for Keratinocyte Host Defense against Herpes Simplex Virus-1.11
316663852020Human Papillomavirus 16 E5 Inhibits Interferon Signaling and Supports Episomal Viral Maintenance.41
319559632020MDA5(+) Dermatomyositis Is Associated with Stronger Skin Type I Interferon Transcriptomic Signature with Upregulation of IFN-κ Transcript.18
323520192020Interferon Kappa Is Important for Keratinocyte Host Defense against Herpes Simplex Virus-1.11
283248052017Limited role of interferon-kappa (IFNK) truncating mutations in common variable immunodeficiency.2

Citation

Dessen P

IFNK (interferon kappa)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51313/ifnk