NTSR2 (neurotensin receptor 2)

2010-02-01  

Identity

HGNC
NTSR2
LOCATION
2p25.1
LOCUSID
23620
ALIAS
NTR2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23620
MIM: 605538
HGNC: 8040
Ensembl: ENSG00000169006

Variants:

dbSNP: 23620
ClinVar: 23620
TCGA: ENSG00000169006
COSMIC: NTSR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169006ENST00000306928O95665

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

References

Pubmed IDYearTitleCitations
379620462024Physiological and Pathological Roles of NTSR2 in Several Organs and Diseases (Review).0
384807832024Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia.0
379620462024Physiological and Pathological Roles of NTSR2 in Several Organs and Diseases (Review).0
384807832024Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia.0
327642782020Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications.5
327642782020Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications.5
307709012019Neurotensin and its receptors mediate neuroendocrine transdifferentiation in prostate cancer.20
307709012019Neurotensin and its receptors mediate neuroendocrine transdifferentiation in prostate cancer.20
290591512018Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis.10
290591512018Neurotensin receptor type 2 protects B-cell chronic lymphocytic leukemia cells from apoptosis.10
284983962017Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells.14
284983962017Diverse expression patterns and tumorigenic role of neurotensin signaling components in colorectal cancer cells.14
262987742015Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells.10
262987742015Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells.10
231097252012Differential expression of neurotensin and specific receptors, NTSR1 and NTSR2, in normal and malignant human B lymphocytes.17

Citation

Dessen P

NTSR2 (neurotensin receptor 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51345