Identity
HGNC
LOCATION
15q13.1
LOCUSID
ALIAS
D15S1518E,HsT16821,LIN-10,MGC:14091,MINT2,X11-BETA,X11L
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 321
MIM: 602712
HGNC: 579
Ensembl: ENSG00000034053
Variants:
dbSNP: 321
ClinVar: 321
TCGA: ENSG00000034053
COSMIC: APBA2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Protein-protein interactions at synapses | REACTOME | R-HSA-6794362 |
| Interactions of neurexins and neuroligins at synapses | REACTOME | R-HSA-6794361 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30988517 | 2019 | A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function. | 6 |
| 31182603 | 2019 | Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype. | 21 |
| 30988517 | 2019 | A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function. | 6 |
| 31182603 | 2019 | Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype. | 21 |
| 28164769 | 2017 | Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients. | 0 |
| 28164769 | 2017 | Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients. | 0 |
| 24385013 | 2014 | Circulating methylated MINT2 promoter DNA is a potential poor prognostic factor in gastric cancer. | 19 |
| 24742670 | 2014 | Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation. | 0 |
| 24385013 | 2014 | Circulating methylated MINT2 promoter DNA is a potential poor prognostic factor in gastric cancer. | 19 |
| 24742670 | 2014 | Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation. | 0 |
| 22222501 | 2012 | Promoter characterization and genomic organization of the human X11β gene APBA2. | 3 |
| 23076970 | 2012 | Gene expression changes in peripheral blood from Chinese Han patients with Tourette syndrome. | 4 |
| 22222501 | 2012 | Promoter characterization and genomic organization of the human X11β gene APBA2. | 3 |
| 23076970 | 2012 | Gene expression changes in peripheral blood from Chinese Han patients with Tourette syndrome. | 4 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
APBA2 (amyloid beta precursor protein binding family A member 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/51371/apba2
