LIPF (lipase F, gastric type)

2010-03-01  

Identity

HGNC
LIPF
LOCATION
10q23.31
LOCUSID
8513
ALIAS
GL,HGL,HLAL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8513
MIM: 601980
HGNC: 6622
Ensembl: ENSG00000182333

Variants:

dbSNP: 8513
ClinVar: 8513
TCGA: ENSG00000182333
COSMIC: LIPF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182333ENST00000238983P07098
ENSG00000182333ENST00000355843P07098
ENSG00000182333ENST00000394375P07098
ENSG00000182333ENST00000608620P07098

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerolipid metabolismKEGGhsa00561
Metabolic pathwaysKEGGhsa01100
Fat digestion and absorptionKEGGko04975
Fat digestion and absorptionKEGGhsa04975
Acylglycerol degradationKEGGhsa_M00098
Acylglycerol degradationKEGGM00098
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Digestion of dietary lipidREACTOMER-HSA-192456

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
286942182017Constitutive expression of human gastric lipase in Pichia pastoris and site-directed mutagenesis of key lid-stabilizing residues.2
286942182017Constitutive expression of human gastric lipase in Pichia pastoris and site-directed mutagenesis of key lid-stabilizing residues.2
274987822016Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer.15
274987822016Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer.15
250599522015Intrahepatic Cholestasis of Pregnancy: mRNAs for LIPF and ELOVL4 Genes Are Not Detectable in Circulating Maternal Plasma.0
250599522015Intrahepatic Cholestasis of Pregnancy: mRNAs for LIPF and ELOVL4 Genes Are Not Detectable in Circulating Maternal Plasma.0
219457022012Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system.6
219457022012Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system.6
208853902011A common haplotype in NAPEPLD is associated with severe obesity in a Norwegian population-based cohort (the HUNT study).10
208853902011A common haplotype in NAPEPLD is associated with severe obesity in a Norwegian population-based cohort (the HUNT study).10
200430752010An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer.36
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?3
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
209651712010Molecular dynamics simulations of human and dog gastric lipases: insights into domain movements.4
200430752010An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer.36

Citation

Dessen P

LIPF (lipase F, gastric type)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51382