POU6F1 (POU class 6 homeobox 1)

2010-03-01  

Identity

HGNC
POU6F1
LOCATION
12q13.13
LOCUSID
5463
ALIAS
BRN5,MPOU,TCFB1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5463
MIM: 618043
HGNC: 9224
Ensembl: ENSG00000184271

Variants:

dbSNP: 5463
ClinVar: 5463
TCGA: ENSG00000184271
COSMIC: POU6F1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184271ENST00000333640A0A1C7CYV8
ENSG00000184271ENST00000550824A0A1C7CYY7
ENSG00000184271ENST00000552305A0A1B0GVK9
ENSG00000184271ENST00000636728A0A1B0GU61

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382677462024POU6F1 promotes ferroptosis by increasing lncRNA-CASC2 transcription to regulate SOCS2/SLC7A11 signaling in gastric cancer.0
382677462024POU6F1 promotes ferroptosis by increasing lncRNA-CASC2 transcription to regulate SOCS2/SLC7A11 signaling in gastric cancer.0
316653132020Aurora kinase A-mediated phosphorylation of mPOU at a specific site drives skeletal muscle differentiation.0
316653132020Aurora kinase A-mediated phosphorylation of mPOU at a specific site drives skeletal muscle differentiation.0
201342652010Transcription factor POU6F1 is important for proliferation of clear cell adenocarcinoma of the ovary and is a potential new molecular target.6
201342652010Transcription factor POU6F1 is important for proliferation of clear cell adenocarcinoma of the ovary and is a potential new molecular target.6
194506912009Structure of human Brn-5 transcription factor in complex with CRH gene promoter.9
198743982009POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary.1
194506912009Structure of human Brn-5 transcription factor in complex with CRH gene promoter.9
198743982009POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovary.1
183236012008Crystallization and preliminary X-ray analysis of human Brn-5 transcription factor in complex with DNA.1
183236012008Crystallization and preliminary X-ray analysis of human Brn-5 transcription factor in complex with DNA.1

Citation

Dessen P

POU6F1 (POU class 6 homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51389