Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55257
MIM: 611157
HGNC: 15866
Ensembl: ENSG00000101189
Variants:
dbSNP: 55257
ClinVar: 55257
TCGA: ENSG00000101189
COSMIC: MRGBP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101189 | ENST00000370487 | Q9NV56 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36208716 | 2022 | MRGBP promotes colorectal cancer metastasis via DKK1/Wnt/β-catenin and NF-kB/p65 pathways mediated EMT. | 3 |
| 36208716 | 2022 | MRGBP promotes colorectal cancer metastasis via DKK1/Wnt/β-catenin and NF-kB/p65 pathways mediated EMT. | 3 |
| 33354938 | 2021 | MRGBP, a member of the NuA4 complex, inhibits DNA double-strand break repair. | 4 |
| 33761715 | 2021 | MRGBP is a potential novel prognostic biomarker and is correlated with immune infiltrates in hepatocellular carcinoma. | 1 |
| 33354938 | 2021 | MRGBP, a member of the NuA4 complex, inhibits DNA double-strand break repair. | 4 |
| 33761715 | 2021 | MRGBP is a potential novel prognostic biomarker and is correlated with immune infiltrates in hepatocellular carcinoma. | 1 |
| 21535316 | 2011 | MRG-binding protein contributes to colorectal cancer development. | 9 |
| 21602893 | 2011 | Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma. | 32 |
| 21535316 | 2011 | MRG-binding protein contributes to colorectal cancer development. | 9 |
| 21602893 | 2011 | Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma. | 32 |
| 20051959 | 2010 | C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer. | 21 |
| 20051959 | 2010 | C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer. | 21 |
| 12963728 | 2003 | Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. | 116 |
| 12963728 | 2003 | Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. | 116 |
Citation
Dessen P
MRGBP (MRG domain binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/51396/mrgbp
