Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79733
MIM: 612047
HGNC: 24727
Ensembl: ENSG00000129173
Variants:
dbSNP: 79733
ClinVar: 79733
TCGA: ENSG00000129173
COSMIC: E2F8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000129173 | ENST00000250024 | A0AVK6 |
| ENSG00000129173 | ENST00000527884 | A0AVK6 |
| ENSG00000129173 | ENST00000532666 | E9PMT9 |
| ENSG00000129173 | ENST00000620009 | A0AVK6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38661062 | 2024 | ENO1 promotes trophoblast invasion regulated by E2F8 in recurrent miscarriage. | 1 |
| 38795825 | 2024 | TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta. | 0 |
| 38661062 | 2024 | ENO1 promotes trophoblast invasion regulated by E2F8 in recurrent miscarriage. | 1 |
| 38795825 | 2024 | TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta. | 0 |
| 37635486 | 2023 | E2F8 knockdown suppresses cell proliferation and induces cell cycle arrest via Wnt/β-Catenin pathway in ovarian cancer. | 0 |
| 37863324 | 2023 | E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. | 1 |
| 37888771 | 2023 | Cyclosporin A inhibits prostate cancer growth through suppression of E2F8 transcription factor in a MELK‑dependent manner. | 1 |
| 37635486 | 2023 | E2F8 knockdown suppresses cell proliferation and induces cell cycle arrest via Wnt/β-Catenin pathway in ovarian cancer. | 0 |
| 37863324 | 2023 | E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. | 1 |
| 37888771 | 2023 | Cyclosporin A inhibits prostate cancer growth through suppression of E2F8 transcription factor in a MELK‑dependent manner. | 1 |
| 36241625 | 2022 | Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation. | 5 |
| 36241625 | 2022 | Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation. | 5 |
| 31733123 | 2020 | RNA-binding protein NONO promotes breast cancer proliferation by post-transcriptional regulation of SKP2 and E2F8. | 47 |
| 31929759 | 2020 | E2F8 regulates the proliferation and invasion through epithelial-mesenchymal transition in cervical cancer. | 14 |
| 31990034 | 2020 | Carcinogenesis effects of E2F transcription factor 8 (E2F8) in hepatocellular carcinoma outcomes: an integrated bioinformatic report. | 4 |
Citation
Dessen P
E2F8 (E2F transcription factor 8)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/51400/e2f8
