Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
CDC45L,CDC45L2,MGORS7,PORC-PI-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8318
MIM: 603465
HGNC: 1739
Ensembl: ENSG00000093009
Variants:
dbSNP: 8318
ClinVar: 8318
TCGA: ENSG00000093009
COSMIC: CDC45
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38467731 | 2024 | A second hotspot for pathogenic exon-skipping variants in CDC45. | 1 |
| 38515458 | 2024 | Validation of CDC45 as a novel biomarker for diagnosis and prognosis of gastric cancer. | 0 |
| 38467731 | 2024 | A second hotspot for pathogenic exon-skipping variants in CDC45. | 1 |
| 38515458 | 2024 | Validation of CDC45 as a novel biomarker for diagnosis and prognosis of gastric cancer. | 0 |
| 37985379 | 2023 | IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification. | 0 |
| 37985379 | 2023 | IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification. | 0 |
| 34931691 | 2022 | Knockdown of circular RNA hsa_circ_0062270 suppresses the progression of melanoma via downregulation of CDC45. | 6 |
| 36082823 | 2022 | Systematic pan‑cancer analysis identifies CDC45 as having an oncogenic role in human cancers. | 6 |
| 34931691 | 2022 | Knockdown of circular RNA hsa_circ_0062270 suppresses the progression of melanoma via downregulation of CDC45. | 6 |
| 36082823 | 2022 | Systematic pan‑cancer analysis identifies CDC45 as having an oncogenic role in human cancers. | 6 |
| 33622998 | 2021 | Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes. | 12 |
| 33639314 | 2021 | A synonymous variant in a non-canonical exon of CDC45 disrupts splicing in two affected sibs with Meier-Gorlin syndrome with craniosynostosis. | 7 |
| 34627193 | 2021 | CircCDC45 promotes the malignant progression of glioblastoma by modulating the miR-485-5p/CSF-1 axis. | 8 |
| 33622998 | 2021 | Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the CDC45 Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes. | 12 |
| 33639314 | 2021 | A synonymous variant in a non-canonical exon of CDC45 disrupts splicing in two affected sibs with Meier-Gorlin syndrome with craniosynostosis. | 7 |
Citation
Dessen P
CDC45 (cell division cycle 45)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51414/cdc45
