GINS3 (GINS complex subunit 3)

2010-04-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
PSF3
FUSION GENES

Other Information

Locus ID:

NCBI: 64785
MIM: 610610
HGNC: 25851
Ensembl: ENSG00000181938

Variants:

dbSNP: 64785
ClinVar: 64785
TCGA: ENSG00000181938
COSMIC: GINS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181938ENST00000318129Q9BRX5
ENSG00000181938ENST00000318129A0A0S2Z5L0
ENSG00000181938ENST00000328514Q9BRX5
ENSG00000181938ENST00000328514A0A0S2Z5L4
ENSG00000181938ENST00000426538Q9BRX5
ENSG00000181938ENST00000426538A0A0S2Z5P2

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
GINS complexKEGGhsa_M00286
GINS complexKEGGM00286
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
S PhaseREACTOMER-HSA-69242
Synthesis of DNAREACTOMER-HSA-69239
DNA strand elongationREACTOMER-HSA-69190
Unwinding of DNAREACTOMER-HSA-176974
DNA ReplicationREACTOMER-HSA-69306

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
356037892022Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.6
358960112022Combined analysis of expression, prognosis and immune infiltration of GINS family genes in human sarcoma.4
356037892022Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.6
358960112022Combined analysis of expression, prognosis and immune infiltration of GINS family genes in human sarcoma.4
304136052018Up-regulated and interrelated expressions of GINS subunits predict poor prognosis in hepatocellular carcinoma.13
304136052018Up-regulated and interrelated expressions of GINS subunits predict poor prognosis in hepatocellular carcinoma.13
280717572017New insights into the GINS complex explain the controversy between existing structural models.8
280717572017New insights into the GINS complex explain the controversy between existing structural models.8
270059772016Psf3 is a prognostic biomarker in lung adenocarcinoma: a larger trial using tissue microarrays of 864 consecutive resections.6
270059772016Psf3 is a prognostic biomarker in lung adenocarcinoma: a larger trial using tissue microarrays of 864 consecutive resections.6
255202512015Adipose tissue gene expression and metabolic health of obese adults.18
262919872015Significant role of Psf3 expression in non-small-cell lung cancer.20
255202512015Adipose tissue gene expression and metabolic health of obese adults.18
262919872015Significant role of Psf3 expression in non-small-cell lung cancer.20
254036842014Partner of Sld five 3: a potential prognostic biomarker for colorectal cancer.5

Citation

Dessen P

GINS3 (GINS complex subunit 3)

Atlas Genet Cytogenet Oncol Haematol. 2010-04-01

Online version: http://atlasgeneticsoncology.org/gene/51419/gins3