Identity
HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
CD305,LAIR-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3903
MIM: 602992
HGNC: 6477
Ensembl: ENSG00000167613
Variants:
dbSNP: 3903
ClinVar: 3903
TCGA: ENSG00000167613
COSMIC: LAIR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38512030 | 2024 | [leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) inhibits proliferation and promotes apoptosis of human HEL cells with JAK2 V617F mutation by blocking the JAK/STAT and PI3K/AKT signaling pathways]. | 0 |
| 38512030 | 2024 | [leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) inhibits proliferation and promotes apoptosis of human HEL cells with JAK2 V617F mutation by blocking the JAK/STAT and PI3K/AKT signaling pathways]. | 0 |
| 35702880 | 2023 | Development and validation of a leukocyte-associated immunoglobulin-like receptor-1 prognostic signature for lower-grade gliomas. | 1 |
| 37634572 | 2023 | LAIR-1 limits macrophage activation in acute inflammatory lung injury. | 2 |
| 37845206 | 2023 | LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines. | 1 |
| 35702880 | 2023 | Development and validation of a leukocyte-associated immunoglobulin-like receptor-1 prognostic signature for lower-grade gliomas. | 1 |
| 37634572 | 2023 | LAIR-1 limits macrophage activation in acute inflammatory lung injury. | 2 |
| 37845206 | 2023 | LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines. | 1 |
| 36293412 | 2022 | Cytotoxic T Cell Expression of Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) in Viral Hepatitis C-Mediated Hepatocellular Carcinoma. | 4 |
| 36293412 | 2022 | Cytotoxic T Cell Expression of Leukocyte-Associated Immunoglobulin-Like Receptor-1 (LAIR-1) in Viral Hepatitis C-Mediated Hepatocellular Carcinoma. | 4 |
| 34244481 | 2021 | Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. | 2 |
| 34244481 | 2021 | Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. | 2 |
| 31843567 | 2020 | Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants. | 8 |
| 31932281 | 2020 | Leukocyte-associated immunoglobulin-like receptor 1 inhibits T-cell signaling by decreasing protein phosphorylation in the T-cell signaling pathway. | 18 |
| 32563267 | 2020 | LAIR-1 overexpression inhibits epithelial-mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism. | 10 |
Citation
Dessen P
LAIR1 (leukocyte associated immunoglobulin like receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51428/lair1
