Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5445
MIM: 602447
HGNC: 9205
Ensembl: ENSG00000105854
Variants:
dbSNP: 5445
ClinVar: 5445
TCGA: ENSG00000105854
COSMIC: PON2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | ||
| PA452229 | antidepressants | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38397445 | 2024 | Contribution of the Paraoxonase-2 Enzyme to Cancer Cell Metabolism and Phenotypes. | 1 |
| 38893310 | 2024 | The Human Paraoxonase 2: An Optimized Procedure for Refolding and Stabilization Facilitates Enzyme Analyses and a Proteomics Approach. | 0 |
| 38397445 | 2024 | Contribution of the Paraoxonase-2 Enzyme to Cancer Cell Metabolism and Phenotypes. | 1 |
| 38893310 | 2024 | The Human Paraoxonase 2: An Optimized Procedure for Refolding and Stabilization Facilitates Enzyme Analyses and a Proteomics Approach. | 0 |
| 36653584 | 2023 | Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation. | 2 |
| 36840500 | 2023 | PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway. | 1 |
| 36897549 | 2023 | Paraoxonase-2 is upregulated in triple negative breast cancer and contributes to tumor progression and chemoresistance. | 14 |
| 36653584 | 2023 | Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation. | 2 |
| 36840500 | 2023 | PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway. | 1 |
| 36897549 | 2023 | Paraoxonase-2 is upregulated in triple negative breast cancer and contributes to tumor progression and chemoresistance. | 14 |
| 34710487 | 2022 | Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells. | 2 |
| 35092416 | 2022 | Insights into the role of paraoxonase 2 in human pathophysiology. | 6 |
| 35286330 | 2022 | Airway epithelial Paraoxonase-2 in obese asthma. | 2 |
| 35460610 | 2022 | Paraoxonase 2 C311S single nucleotide polymorphism is associated with type C lesions in coronary atherosclerosis. | 0 |
| 36076661 | 2022 | Association of Paraoxonase-2 (C1053G) Gene Polymorphism with the Expression of Paraoxonase-2 Gene in Patients of Ischemic Stroke - A Pilot Study in Indian Population. | 1 |
Citation
Dessen P
PON2 (paraoxonase 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51467/pon2
