Identity
HGNC
LOCATION
8q24.21
LOCUSID
ALIAS
OCT4-PG1,OCT4PG1,OTF3C,OTF3P1,POU5F1P1,POU5F1P4,POU5FLC20,POU5FLC8
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5462
MIM: 615739
HGNC: 9223
Ensembl: ENSG00000212993
Variants:
dbSNP: 5462
ClinVar: 5462
TCGA: ENSG00000212993
COSMIC: POU5F1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000212993 | ENST00000465342 | Q06416 |
| ENSG00000212993 | ENST00000645438 | Q06416 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | KEGG | hsa04550 |
| Signaling pathways regulating pluripotency of stem cells | KEGG | ko04550 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35987910 | 2022 | Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis. | 5 |
| 35987910 | 2022 | Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis. | 5 |
| 34934770 | 2021 | Recurrent Superenhancer of the Oncogene POU5F1B in Colorectal Cancers. | 1 |
| 34934770 | 2021 | Recurrent Superenhancer of the Oncogene POU5F1B in Colorectal Cancers. | 1 |
| 30762028 | 2019 | The Octamer-Binding Transcription Factor 4 (OCT4) Pseudogene, POU Domain Class 5 Transcription Factor 1B (POU5F1B), is Upregulated in Cervical Cancer and Down-Regulation Inhibits Cell Proliferation and Migration and Induces Apoptosis in Cervical Cancer Cell Lines. | 8 |
| 30763293 | 2019 | Knockdown of Long Noncoding RNA POU5F1B Promotes Radiosensitivity in Esophageal Carcinoma. | 1 |
| 31271156 | 2019 | Low Expression of Pseudogene POU5F1B Affects Diagnosis and Prognosis in Acute Myeloid Leukemia (AML). | 6 |
| 30762028 | 2019 | The Octamer-Binding Transcription Factor 4 (OCT4) Pseudogene, POU Domain Class 5 Transcription Factor 1B (POU5F1B), is Upregulated in Cervical Cancer and Down-Regulation Inhibits Cell Proliferation and Migration and Induces Apoptosis in Cervical Cancer Cell Lines. | 8 |
| 30763293 | 2019 | Knockdown of Long Noncoding RNA POU5F1B Promotes Radiosensitivity in Esophageal Carcinoma. | 1 |
| 31271156 | 2019 | Low Expression of Pseudogene POU5F1B Affects Diagnosis and Prognosis in Acute Myeloid Leukemia (AML). | 6 |
| 29454285 | 2018 | POU5F1B promotes hepatocellular carcinoma proliferation by activating AKT. | 19 |
| 29620155 | 2018 | Differential expression of Oct3/4 in human breast cancer and normal tissues. | 11 |
| 29454285 | 2018 | POU5F1B promotes hepatocellular carcinoma proliferation by activating AKT. | 19 |
| 29620155 | 2018 | Differential expression of Oct3/4 in human breast cancer and normal tissues. | 11 |
| 28463958 | 2017 | Prospective study of DNA methylation at chromosome 8q24 in peripheral blood and prostate cancer risk. | 10 |
Citation
Dessen P
POU5F1B (POU class 5 homeobox 1B)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51472/pou5f1b
