Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50511
MIM: 604759
HGNC: 18130
Ensembl: ENSG00000139351
Variants:
dbSNP: 50511
ClinVar: 50511
TCGA: ENSG00000139351
COSMIC: SYCP3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Homologous recombination | KEGG | ko03440 |
| Homologous recombination | KEGG | hsa03440 |
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic synapsis | REACTOME | R-HSA-1221632 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28287952 | 2017 | Single-molecule observation of DNA compaction by meiotic protein SYCP3. | 17 |
| 28623914 | 2017 | Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis. | 14 |
| 28745000 | 2017 | SYCP3 regulates strand invasion activities of RAD51 and DMC1. | 10 |
| 28287952 | 2017 | Single-molecule observation of DNA compaction by meiotic protein SYCP3. | 17 |
| 28623914 | 2017 | Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis. | 14 |
| 28745000 | 2017 | SYCP3 regulates strand invasion activities of RAD51 and DMC1. | 10 |
| 24905095 | 2014 | Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. | 17 |
| 24950965 | 2014 | A molecular model for the role of SYCP3 in meiotic chromosome organisation. | 64 |
| 25059562 | 2014 | The T657C polymorphism on the SYCP3 gene is associated with recurrent pregnancy loss. | 11 |
| 24905095 | 2014 | Synaptonemal complex protein 3 is a prognostic marker in cervical cancer. | 17 |
| 24950965 | 2014 | A molecular model for the role of SYCP3 in meiotic chromosome organisation. | 64 |
| 25059562 | 2014 | The T657C polymorphism on the SYCP3 gene is associated with recurrent pregnancy loss. | 11 |
| 22670862 | 2013 | Investigation of mutations in the synaptonemal complex protein 3 (SYCP3) gene among azoospermic infertile male patients in the Turkish population. | 7 |
| 23069255 | 2013 | Synaptonemal complex protein 3 as a novel prognostic marker in early stage non-small cell lung cancer. | 21 |
| 23100464 | 2013 | Mutation screening of AURKB and SYCP3 in patients with reproductive problems. | 6 |
Citation
Dessen P
SYCP3 (synaptonemal complex protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51478/sycp3
