Identity
HGNC
LOCATION
14q24.1
LOCUSID
ALIAS
FYVE-CENT,SPG15
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23503
MIM: 612012
HGNC: 20761
Ensembl: ENSG00000072121
Variants:
dbSNP: 23503
ClinVar: 23503
TCGA: ENSG00000072121
COSMIC: ZFYVE26
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000072121 | ENST00000347230 | Q68DK2 |
| ENSG00000072121 | ENST00000554557 | G3V230 |
| ENSG00000072121 | ENST00000555452 | G3V2D8 |
| ENSG00000072121 | ENST00000557306 | A0A2H2FF08 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36315648 | 2023 | The clinical and molecular spectrum of ZFYVE26-associated hereditary spastic paraplegia: SPG15. | 4 |
| 36315648 | 2023 | The clinical and molecular spectrum of ZFYVE26-associated hereditary spastic paraplegia: SPG15. | 4 |
| 33637369 | 2022 | Investigating ZFYVE26 mutations in a Taiwanese cohort with hereditary spastic paraplegia. | 3 |
| 33637369 | 2022 | Investigating ZFYVE26 mutations in a Taiwanese cohort with hereditary spastic paraplegia. | 3 |
| 33771085 | 2021 | Description of clinical features and genetic analysis of one ultra-rare (SPG64) and two common forms (SPG5A and SPG15) of hereditary spastic paraplegia families. | 4 |
| 33771085 | 2021 | Description of clinical features and genetic analysis of one ultra-rare (SPG64) and two common forms (SPG5A and SPG15) of hereditary spastic paraplegia families. | 4 |
| 32006740 | 2020 | Rare novel CYP2U1 and ZFYVE26 variants identified in two Pakistani families with spastic paraplegia. | 7 |
| 32006740 | 2020 | Rare novel CYP2U1 and ZFYVE26 variants identified in two Pakistani families with spastic paraplegia. | 7 |
| 30081747 | 2019 | ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis. | 29 |
| 30081747 | 2019 | ZFYVE26/SPASTIZIN and SPG11/SPATACSIN mutations in hereditary spastic paraplegia types AR-SPG15 and AR-SPG11 have different effects on autophagy and endocytosis. | 29 |
| 29726929 | 2018 | Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias. | 26 |
| 29726929 | 2018 | Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias. | 26 |
| 26492578 | 2016 | Novel mutations in genes causing hereditary spastic paraplegia and Charcot-Marie-Tooth neuropathy identified by an optimized protocol for homozygosity mapping based on whole-exome sequencing. | 23 |
| 26492578 | 2016 | Novel mutations in genes causing hereditary spastic paraplegia and Charcot-Marie-Tooth neuropathy identified by an optimized protocol for homozygosity mapping based on whole-exome sequencing. | 23 |
| 24284334 | 2014 | ZFYVE26/SPASTIZIN: a close link between complicated hereditary spastic paraparesis and autophagy. | 11 |
Citation
Dessen P
ZFYVE26 (zinc finger FYVE-type containing 26)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51489/zfyve26
