PDLIM2 (PDZ and LIM domain 2)

2010-05-01  

Identity

HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
MYSTIQUE,SLIM
FUSION GENES

Other Information

Locus ID:

NCBI: 64236
MIM: 609722
HGNC: 13992
Ensembl: ENSG00000120913

Variants:

dbSNP: 64236
ClinVar: 64236
TCGA: ENSG00000120913
COSMIC: PDLIM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120913ENST00000265810Q96JY6
ENSG00000120913ENST00000308354Q96JY6
ENSG00000120913ENST00000339162Q96JY6
ENSG00000120913ENST00000397760Q96JY6
ENSG00000120913ENST00000397761Q96JY6
ENSG00000120913ENST00000409141Q96JY6
ENSG00000120913ENST00000409417Q96JY6
ENSG00000120913ENST00000416159F8WFB8
ENSG00000120913ENST00000426493C9J0X3
ENSG00000120913ENST00000429812C9K0F0
ENSG00000120913ENST00000436754C9J760
ENSG00000120913ENST00000443561A0A087WUQ1
ENSG00000120913ENST00000448520A0A087WXJ0
ENSG00000120913ENST00000452226C9JS55
ENSG00000120913ENST00000456545C9JSR2
ENSG00000120913ENST00000464275B3KPU0
ENSG00000120913ENST00000614502B3KPU0
ENSG00000120913ENST00000616289A0A087WU48
ENSG00000120913ENST00000622702A0A087WVI1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371706682023PDLIM2 can inactivate the TGF-β/Smad pathway to inhibit the malignant behavior of ovarian cancer cells.3
371706682023PDLIM2 can inactivate the TGF-β/Smad pathway to inhibit the malignant behavior of ovarian cancer cells.3
347137692022Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis.6
351217702022Systematic evaluation of the prognostic and immunological role of PDLIM2 across 33 cancer types.3
357070022022High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration.6
347137692022Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis.6
351217702022Systematic evaluation of the prognostic and immunological role of PDLIM2 across 33 cancer types.3
357070022022High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration.6
342285042021Central Nervous System-Infecting Pathogens Escherichia coli and Cryptococcus neoformans Exploit the Host Pdlim2 for Intracellular Traversal and Exocytosis in the Blood-Brain Barrier.0
342285042021Central Nervous System-Infecting Pathogens Escherichia coli and Cryptococcus neoformans Exploit the Host Pdlim2 for Intracellular Traversal and Exocytosis in the Blood-Brain Barrier.0
326218482020PDLIM2 acts as a cancer suppressor gene in non-small cell lung cancer via the down regulation of NF-κB signaling.5
326218482020PDLIM2 acts as a cancer suppressor gene in non-small cell lung cancer via the down regulation of NF-κB signaling.5
308859802019PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer.11
312229322019Systematic profiling identifies PDLIM2 as a novel prognostic predictor for oesophageal squamous cell carcinoma (ESCC).10
317579432019Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.24

Citation

Dessen P

PDLIM2 (PDZ and LIM domain 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51491/pdlim2