Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
SMT3IP1,SSP3,Ulp1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26168
MIM: 612844
HGNC: 17862
Ensembl: ENSG00000161956
Variants:
dbSNP: 26168
ClinVar: 26168
TCGA: ENSG00000161956
COSMIC: SENP3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38273178 | 2024 | SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression. | 0 |
| 38383667 | 2024 | SENP3 mediates the activation of the Wnt/β-catenin signaling pathway to accelerate the growth and metastasis of oesophagal squamous cell carcinoma in mice. | 0 |
| 38273178 | 2024 | SENP3 Promotes Mantle Cell Lymphoma Development through Regulating Wnt10a Expression. | 0 |
| 38383667 | 2024 | SENP3 mediates the activation of the Wnt/β-catenin signaling pathway to accelerate the growth and metastasis of oesophagal squamous cell carcinoma in mice. | 0 |
| 36840491 | 2023 | Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage. | 1 |
| 37188742 | 2023 | SUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1. | 1 |
| 36840491 | 2023 | Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage. | 1 |
| 37188742 | 2023 | SUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1. | 1 |
| 35275026 | 2022 | Iron chelation promotes mitophagy through SENP3-mediated deSUMOylation of FIS1. | 4 |
| 35623300 | 2022 | SUMO-specific protease SENP3 enhances MDM2-mediated ubiquitination of PARIS/ZNF746 in HeLa cells. | 1 |
| 36050397 | 2022 | Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin. | 3 |
| 36227136 | 2022 | SENP3 affects the expression of PYCR1 to promote bladder cancer proliferation and EMT transformation by deSUMOylation of STAT3. | 3 |
| 35275026 | 2022 | Iron chelation promotes mitophagy through SENP3-mediated deSUMOylation of FIS1. | 4 |
| 35623300 | 2022 | SUMO-specific protease SENP3 enhances MDM2-mediated ubiquitination of PARIS/ZNF746 in HeLa cells. | 1 |
| 36050397 | 2022 | Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin. | 3 |
Citation
Dessen P
SENP3 (SUMO specific peptidase 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51505/senp3
