INHBE (inhibin subunit beta E)

2010-06-01  

Identity

HGNC
LOCATION
12q13.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 83729
MIM: 612031
HGNC: 24029
Ensembl: ENSG00000139269

Variants:

dbSNP: 83729
ClinVar: 83729
TCGA: ENSG00000139269
COSMIC: INHBE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139269ENST00000266646P58166
ENSG00000139269ENST00000547970F8VNP4

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
TGF-beta signaling pathwayKEGGko04350
Cytokine-cytokine receptor interactionKEGGhsa04060
TGF-beta signaling pathwayKEGGhsa04350
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Activin signalingKEGGhsa_M00681
Activin signalingKEGGM00681
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Peptide hormone biosynthesisREACTOMER-HSA-209952
Glycoprotein hormonesREACTOMER-HSA-209822

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379225702023Identification and validation of INHBE and P4HA1 as hub genes in non-alcoholic fatty liver disease.2
379225702023Identification and validation of INHBE and P4HA1 as hub genes in non-alcoholic fatty liver disease.2
345152602022The Significance of INHBE Expression in the Cancer Cells of Clear-Cell Renal Cell Carcinoma.3
358965312022Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity.14
359992172022Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.17
345152602022The Significance of INHBE Expression in the Cancer Cells of Clear-Cell Renal Cell Carcinoma.3
358965312022Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity.14
359992172022Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.17
295964632018Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples.22
295964632018Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples.22
250624512014Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.18
250624512014Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.18
235800132013The inhibin-βC subunit is down-regulated, while inhibin-βE is up-regulated by interferon-β1a in Ishikawa carcinoma cell line.4
235800132013The inhibin-βC subunit is down-regulated, while inhibin-βE is up-regulated by interferon-β1a in Ishikawa carcinoma cell line.4
200123052010Inhibin/activin-betaC and -betaE subunits in the Ishikawa human endometrial adenocarcinoma cell line.8

Citation

Dessen P

INHBE (inhibin subunit beta E)

Atlas Genet Cytogenet Oncol Haematol. 2010-06-01

Online version: http://atlasgeneticsoncology.org/gene/51532/gene-fusions-explorer/js/lib/gene-fusions/?id=51532