Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
PDA2,PDI,PDIP,PDIR
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64714
MIM: 608012
HGNC: 14180
Ensembl: ENSG00000185615
Variants:
dbSNP: 64714
ClinVar: 64714
TCGA: ENSG00000185615
COSMIC: PDIA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185615 | ENST00000219406 | Q13087 |
| ENSG00000185615 | ENST00000404312 | Q13087 |
| ENSG00000185615 | ENST00000435833 | Q4TT65 |
| ENSG00000185615 | ENST00000456379 | H0Y4J5 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38589675 | 2024 | PDIA2 has a dual function in promoting androgen deprivation therapy induced venous thrombosis events and castrate resistant prostate cancer progression. | 0 |
| 38589675 | 2024 | PDIA2 has a dual function in promoting androgen deprivation therapy induced venous thrombosis events and castrate resistant prostate cancer progression. | 0 |
| 37017923 | 2023 | The involvement of PDIA2 gene in the progression of renal cell carcinoma is potentially through regulation of JNK signaling pathway. | 0 |
| 37978154 | 2023 | Protein Disulfide Isomerase A2 Is Correlated with Immune Infiltrates and Is a Novel Prognostic Biomarker in Glioma Patients. | 0 |
| 37017923 | 2023 | The involvement of PDIA2 gene in the progression of renal cell carcinoma is potentially through regulation of JNK signaling pathway. | 0 |
| 37978154 | 2023 | Protein Disulfide Isomerase A2 Is Correlated with Immune Infiltrates and Is a Novel Prognostic Biomarker in Glioma Patients. | 0 |
| 34403458 | 2021 | De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation. | 2 |
| 34403458 | 2021 | De-dimerization of PTB is catalyzed by PDI and is involved in the regulation of p53 translation. | 2 |
| 32102847 | 2020 | Non-native proteins inhibit the ER oxidoreductin 1 (Ero1)-protein disulfide-isomerase relay when protein folding capacity is exceeded. | 6 |
| 32102847 | 2020 | Non-native proteins inhibit the ER oxidoreductin 1 (Ero1)-protein disulfide-isomerase relay when protein folding capacity is exceeded. | 6 |
| 28810662 | 2017 | Galectin-9 binds to O-glycans on protein disulfide isomerase. | 16 |
| 28810662 | 2017 | Galectin-9 binds to O-glycans on protein disulfide isomerase. | 16 |
| 27197150 | 2016 | Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma. | 53 |
| 27197150 | 2016 | Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma. | 53 |
| 25631539 | 2015 | Protein disulphide-isomerase A2 regulated intracellular tissue factor mobilisation in migrating human vascular smooth muscle cells. | 5 |
Citation
Dessen P
PDIA2 (protein disulfide isomerase family A member 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51536/pdia2
