NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1)

2010-07-01  

Identity

HGNC
NUCKS1
LOCATION
1q32.1
LOCUSID
64710
ALIAS
JC7,NUCKS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64710
MIM: 611912
HGNC: 29923
Ensembl: ENSG00000069275

Variants:

dbSNP: 64710
ClinVar: 64710
TCGA: ENSG00000069275
COSMIC: NUCKS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000069275ENST00000367142Q9H1E3

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
336019272023NUCKS1 Acts as a Promising Novel Biomarker for the Prognosis of Patients with Hepatocellular Carcinoma.4
372269322023NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.3
375827722023Roles of increased NUCKS1 expression in endometriosis.1
336019272023NUCKS1 Acts as a Promising Novel Biomarker for the Prognosis of Patients with Hepatocellular Carcinoma.4
372269322023NUCKS1 promotes the progression of colorectal cancer via activating PI3K/AKT/mTOR signaling pathway.3
375827722023Roles of increased NUCKS1 expression in endometriosis.1
348505702022CircRNA circ_0008037 facilitates tumor growth and the Warburg effect via upregulating NUCKS1 by binding to miR-433-3p in non-small cell lung cancer.6
350697842022miR-641 Inhibited Cell Proliferation and Induced Apoptosis by Targeting NUCKS1/PI3K/AKT Signaling Pathway in Breast Cancer.7
348505702022CircRNA circ_0008037 facilitates tumor growth and the Warburg effect via upregulating NUCKS1 by binding to miR-433-3p in non-small cell lung cancer.6
350697842022miR-641 Inhibited Cell Proliferation and Induced Apoptosis by Targeting NUCKS1/PI3K/AKT Signaling Pathway in Breast Cancer.7
336839702021Upregulation of NUCKS1 in Lung Adenocarcinoma is Associated with a Poor Prognosis.5
340301742021Nucks1 gene polymorphism rs823114 is associated with the positive symptoms and neurocognitive function of patients with schizophrenia in parts of southern China.0
341527082021NUCKS Promotes the Proliferation, Migration and Invasion of Lung Cancer Cells Through Pi3k/Akt Signalling Pathway.2
348452292021The NUCKS1-SKP2-p21/p27 axis controls S phase entry.15
336839702021Upregulation of NUCKS1 in Lung Adenocarcinoma is Associated with a Poor Prognosis.5

Citation

Dessen P

NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51557