WDR3 (WD repeat domain 3)

2010-08-01  

Identity

HGNC
LOCATION
1p12
LOCUSID
ALIAS
DIP2,UTP12
FUSION GENES

Other Information

Locus ID:

NCBI: 10885
MIM: 604737
HGNC: 12755
Ensembl: ENSG00000065183

Variants:

dbSNP: 10885
ClinVar: 10885
TCGA: ENSG00000065183
COSMIC: WDR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000065183ENST00000349139Q9UNX4
ENSG00000065183ENST00000349139Q5TDG3
ENSG00000065183ENST00000369441Q6PDA5

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

References

Pubmed IDYearTitleCitations
369051062023WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A.1
369051062023WDR3 promotes stem cell-like properties in prostate cancer by inhibiting USF2-mediated transcription of RASSF1A.1
336485452021Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.7
336485452021Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.7
293094332018Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population.0
293094332018Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population.0
230497462012Possible role of the WDR3 gene on genome stability in thyroid cancer patients.2
230497462012Possible role of the WDR3 gene on genome stability in thyroid cancer patients.2
203926982010Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.20
205789022010WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.7
205789022010WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.7
203926982010Ribosomal 18 S RNA processing by the IGF-I-responsive WDR3 protein is integrated with p53 function in cancer cell proliferation.20
205789022010WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.7
205789022010WDR3 gene haplotype is associated with thyroid cancer risk in a Spanish population.7

Citation

Dessen P

WDR3 (WD repeat domain 3)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51576/css/gene-fusions-explorer/