Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9960
MIM: 604728
HGNC: 12626
Ensembl: ENSG00000140455
Variants:
dbSNP: 9960
ClinVar: 9960
TCGA: ENSG00000140455
COSMIC: USP3
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37921189 | 2024 | USP3 inhibition is Active Against Chemo-resistant Hepatocellular Carcinoma Anchorage-independent Growth via Suppressing Wnt/β-catenin. | 0 |
| 38502867 | 2024 | USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis. | 0 |
| 38531846 | 2024 | USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway. | 1 |
| 38651282 | 2024 | USP3: Key deubiquitylation enzyme in human diseases. | 1 |
| 37921189 | 2024 | USP3 inhibition is Active Against Chemo-resistant Hepatocellular Carcinoma Anchorage-independent Growth via Suppressing Wnt/β-catenin. | 0 |
| 38502867 | 2024 | USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis. | 0 |
| 38531846 | 2024 | USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the PI3K/AKT signaling pathway. | 1 |
| 38651282 | 2024 | USP3: Key deubiquitylation enzyme in human diseases. | 1 |
| 37170124 | 2023 | CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis. | 5 |
| 37170124 | 2023 | CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis. | 5 |
| 36574218 | 2022 | Deubiquitinase ubiquitin-specific protease 3 (USP3) inhibits HIV-1 replication via promoting APOBEC3G (A3G) expression in both enzyme activity-dependent and -independent manners. | 2 |
| 36574218 | 2022 | Deubiquitinase ubiquitin-specific protease 3 (USP3) inhibits HIV-1 replication via promoting APOBEC3G (A3G) expression in both enzyme activity-dependent and -independent manners. | 2 |
| 33767157 | 2021 | An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability. | 29 |
| 34070420 | 2021 | Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells. | 4 |
| 34758762 | 2021 | Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma. | 11 |
Citation
Dessen P
USP3 (ubiquitin specific peptidase 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-08-01
Online version: http://atlasgeneticsoncology.org/gene/51611/usp3
