VWCE (von Willebrand factor C and EGF domains)

2010-08-01  

Identity

HGNC
VWCE
LOCATION
11q12.2
LOCUSID
220001
ALIAS
URG11,VWC1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 220001
MIM: 611115
HGNC: 26487
Ensembl: ENSG00000167992

Variants:

dbSNP: 220001
ClinVar: 220001
TCGA: ENSG00000167992
COSMIC: VWCE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167992ENST00000301770Q96DN2
ENSG00000167992ENST00000335613Q96DN2
ENSG00000167992ENST00000535599B4DS56
ENSG00000167992ENST00000535710B4DY31
ENSG00000167992ENST00000613271A0A087WVD8

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
308646782019URG11 promotes proliferation and induced apoptosis of LNCaP cells.3
308646782019URG11 promotes proliferation and induced apoptosis of LNCaP cells.3
297495202018Silencing of URG11 expression inhibits the proliferation and epithelial‑mesenchymal transition in benign prostatic hyperplasia cells via the RhoA/ROCK1 pathway.8
299556002018URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion.8
297495202018Silencing of URG11 expression inhibits the proliferation and epithelial‑mesenchymal transition in benign prostatic hyperplasia cells via the RhoA/ROCK1 pathway.8
299556002018URG11 Regulates Prostate Cancer Cell Proliferation, Migration, and Invasion.8
274581012016Knockdown of Upregulated Gene 11 (URG11) Inhibits Proliferation, Invasion, and β-Catenin Expression in Non-Small Cell Lung Cancer Cells.5
274581012016Knockdown of Upregulated Gene 11 (URG11) Inhibits Proliferation, Invasion, and β-Catenin Expression in Non-Small Cell Lung Cancer Cells.5
265223622015[Increased expression URG11 in hepatocellular carcinoma tissues promotes the growth of hepatocellular carcinoma cells].2
265223622015[Increased expression URG11 in hepatocellular carcinoma tissues promotes the growth of hepatocellular carcinoma cells].2
249300072014URG11 predicts poor prognosis of pancreatic cancer by enhancing epithelial-mesenchymal transition-driven invasion.6
249300072014URG11 predicts poor prognosis of pancreatic cancer by enhancing epithelial-mesenchymal transition-driven invasion.6
238281642013Association of URG11 and Twist with clinical pathological characteristics and prognosis in patients with IgA nephropathy.4
238281642013Association of URG11 and Twist with clinical pathological characteristics and prognosis in patients with IgA nephropathy.4
194138862010URG11 promotes gastric cancer growth and invasion by activation of beta-catenin signalling pathway.14

Citation

Dessen P

VWCE (von Willebrand factor C and EGF domains)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51615