LIPG (lipase G, endothelial type)

2010-09-01  

Identity

HGNC
LIPG
LOCATION
18q21.1
LOCUSID
9388
ALIAS
EDL,EL,PRO719
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9388
MIM: 603684
HGNC: 6623
Ensembl: ENSG00000101670

Variants:

dbSNP: 9388
ClinVar: 9388
TCGA: ENSG00000101670
COSMIC: LIPG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101670ENST00000261292Q9Y5X9
ENSG00000101670ENST00000261292A0A024R2B5
ENSG00000101670ENST00000427224B4DTR8
ENSG00000101670ENST00000577628J3QQQ0
ENSG00000101670ENST00000579750A0A075B751
ENSG00000101670ENST00000580036Q9Y5X9
ENSG00000101670ENST00000583083J3KTN7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerolipid metabolismKEGGhsa00561
Metabolic pathwaysKEGGhsa01100
Acylglycerol degradationKEGGhsa_M00098
Acylglycerol degradationKEGGM00098
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Digestion of dietary lipidREACTOMER-HSA-192456

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383790262024Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins.0
383790262024Endothelial lipase variant T111I does not alter inhibition by angiopoietin-like proteins.0
366066682023Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B/mechanistic target of rapamycin kinase signalling pathway.1
374172992023Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis.1
366066682023Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/protein kinase B/mechanistic target of rapamycin kinase signalling pathway.1
374172992023Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis.1
325721772021LIPG: an inflammation and cancer modulator.6
334799162021Case-Control Study and Meta-Analysis of the Association Between LIPG rs9958947 SNP and Stroke Risk.0
338823212021Roles of endothelial lipase gene related single nucleotide polymorphisms in patients with coronary artery disease.1
340019442021LIPG endothelial lipase and breast cancer risk by subtypes.1
325721772021LIPG: an inflammation and cancer modulator.6
334799162021Case-Control Study and Meta-Analysis of the Association Between LIPG rs9958947 SNP and Stroke Risk.0
338823212021Roles of endothelial lipase gene related single nucleotide polymorphisms in patients with coronary artery disease.1
340019442021LIPG endothelial lipase and breast cancer risk by subtypes.1
319234672020Endothelial lipase increases eNOS activating capacity of high-density lipoprotein.8

Citation

Dessen P

LIPG (lipase G, endothelial type)

Atlas Genet Cytogenet Oncol Haematol. 2010-09-01

Online version: http://atlasgeneticsoncology.org/gene/51665