ATAD3A (ATPase family AAA domain containing 3A)

2010-09-01  

Identity

HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
HAYOS,PHRINL
FUSION GENES

Other Information

Locus ID:

NCBI: 55210
MIM: 612316
HGNC: 25567
Ensembl: ENSG00000197785

Variants:

dbSNP: 55210
ClinVar: 55210
TCGA: ENSG00000197785
COSMIC: ATAD3A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197785ENST00000339113H0Y2W2
ENSG00000197785ENST00000378755Q9NVI7
ENSG00000197785ENST00000378756Q9NVI7
ENSG00000197785ENST00000400830Q5SV16
ENSG00000197785ENST00000536055Q9NVI7

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380508262024Identification of ATAD3A as a key regulator in non-small cell lung cancer by promoting STAT3-induced cell proliferation and tumor angiogenesis.0
380922752024"ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane".0
380508262024Identification of ATAD3A as a key regulator in non-small cell lung cancer by promoting STAT3-induced cell proliferation and tumor angiogenesis.0
380922752024"ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane".0
366273482023Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria.7
370955542023ATAD3A-related pontocerebellar hypoplasia: new patients and insights into phenotypic variability.2
380182912023The value of ATAD3A as a potential biomarker for bladder cancer.1
366273482023Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria.7
370955542023ATAD3A-related pontocerebellar hypoplasia: new patients and insights into phenotypic variability.2
380182912023The value of ATAD3A as a potential biomarker for bladder cancer.1
362891902022The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.13
362891902022The oncoprotein MUC1 facilitates breast cancer progression by promoting Pink1-dependent mitophagy via ATAD3A destabilization.13
335805142021ATAD3A stabilizes GRP78 to suppress ER stress for acquired chemoresistance in colorectal cancer.12
338458822021Functional interpretation of ATAD3A variants in neuro-mitochondrial phenotypes.13
343876512021Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A.24

Citation

Dessen P

ATAD3A (ATPase family AAA domain containing 3A)

Atlas Genet Cytogenet Oncol Haematol. 2010-09-01

Online version: http://atlasgeneticsoncology.org/gene/51672/atad3a