Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2151
MIM: 601919
HGNC: 3539
Ensembl: ENSG00000164220
Variants:
dbSNP: 2151
ClinVar: 2151
TCGA: ENSG00000164220
COSMIC: F2RL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164220 | ENST00000296641 | O00254 |
| ENSG00000164220 | ENST00000504899 | O00254 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26729042 | 2016 | Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cells. | 4 |
| 26729042 | 2016 | Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cells. | 4 |
| 26742564 | 2015 | Thrombin stimulates insulin secretion via protease-activated receptor-3. | 10 |
| 26742564 | 2015 | Thrombin stimulates insulin secretion via protease-activated receptor-3. | 10 |
| 23921961 | 2014 | Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein. | 9 |
| 24699825 | 2014 | PAR-3 knockdown enhances adhesion rate of PANC-1 cells via increased expression of integrinαv and E-cadherin. | 4 |
| 25320242 | 2014 | Noncanonical PAR3 activation by factor Xa identifies a novel pathway for Tie2 activation and stabilization of vascular integrity. | 22 |
| 23921961 | 2014 | Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein. | 9 |
| 24699825 | 2014 | PAR-3 knockdown enhances adhesion rate of PANC-1 cells via increased expression of integrinαv and E-cadherin. | 4 |
| 25320242 | 2014 | Noncanonical PAR3 activation by factor Xa identifies a novel pathway for Tie2 activation and stabilization of vascular integrity. | 22 |
| 23739922 | 2013 | Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis. | 13 |
| 23788139 | 2013 | Novel mechanisms for activated protein C cytoprotective activities involving noncanonical activation of protease-activated receptor 3. | 50 |
| 23739922 | 2013 | Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis. | 13 |
| 23788139 | 2013 | Novel mechanisms for activated protein C cytoprotective activities involving noncanonical activation of protease-activated receptor 3. | 50 |
| 22541814 | 2012 | Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways. | 12 |
Citation
Dessen P
F2RL2 (coagulation factor II thrombin receptor like 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51702/f2rl2
