CELA3B (chymotrypsin like elastase 3B)

2010-10-01 Affiliation

Identity

HGNC

CELA3B

LOCATION

1p36.12

LOCUSID

23436

ALIAS

CBPP,ELA3B

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 23436
MIM: 618694
HGNC: 15945
Ensembl: ENSG00000219073

Variants:

dbSNP: 23436
ClinVar: 23436
TCGA: ENSG00000219073
COSMIC: CELA3B

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000219073	ENST00000337107	P08861
ENSG00000219073	ENST00000400277	A0A0A0MSA6

Expression (GTEx)

5000

10000

15000

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Pancreatic secretion	KEGG	ko04972
Pancreatic secretion	KEGG	hsa04972
Protein digestion and absorption	KEGG	ko04974
Protein digestion and absorption	KEGG	hsa04974

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36610873	2023	Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience.	2
37307306	2023	Does the Complex of CELA3B Variants With Other Pancreatitis-Related Genes Affect Developing Childhood Pancreatitis?	0
36610873	2023	Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience.	2
37307306	2023	Does the Complex of CELA3B Variants With Other Pancreatitis-Related Genes Affect Developing Childhood Pancreatitis?	0
33565216	2021	The reversion variant (p.Arg90Leu) at the evolutionarily adaptive p.Arg90 site in CELA3B predisposes to chronic pancreatitis.	2
33565216	2021	The reversion variant (p.Arg90Leu) at the evolutionarily adaptive p.Arg90 site in CELA3B predisposes to chronic pancreatitis.	2
31369399	2019	Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.	7
31369399	2019	Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.	7
30106003	2018	Fecal pancreatic elastase-1 and erythrocyte magnesium levels in diabetes type 1 and type 2.	1
30106003	2018	Fecal pancreatic elastase-1 and erythrocyte magnesium levels in diabetes type 1 and type 2.	1
27069032	2016	Pancreatic Elastase Levels in Feces As A Marker of Exocrine Pancreatic Function in Patients With Diabetes Mellitus.	3
27358403	2016	Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.	18
27999401	2016	Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis.	7
27069032	2016	Pancreatic Elastase Levels in Feces As A Marker of Exocrine Pancreatic Function in Patients With Diabetes Mellitus.	3
27358403	2016	Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2.	18

Citation

Dessen P

CELA3B (chymotrypsin like elastase 3B)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51704