Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
ALS10,TDP-43
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23435
MIM: 605078
HGNC: 11571
Ensembl: ENSG00000120948
Variants:
dbSNP: 23435
ClinVar: 23435
TCGA: ENSG00000120948
COSMIC: TARDBP
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37669322 | 2024 | Cross-seeding by prion protein inactivates TDP-43. | 3 |
| 37741764 | 2024 | Identifying and Diagnosing TDP-43 Neurodegenerative Diseases in Psychiatry. | 1 |
| 37793650 | 2024 | Colocalization of TDP-43 and stress granules at the early stage of TDP-43 aggregation in amyotrophic lateral sclerosis. | 2 |
| 37855870 | 2024 | Disease survival and progression in TARDBP ALS patients from Sardinia, Italy. | 1 |
| 38079474 | 2024 | The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis. | 2 |
| 38115557 | 2024 | Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia. | 1 |
| 38175301 | 2024 | Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease. | 5 |
| 38178578 | 2024 | Phosphomimetic substitutions in TDP-43's transiently α-helical region suppress phase separation. | 3 |
| 38183652 | 2024 | TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis. | 5 |
| 38232138 | 2024 | TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. | 4 |
| 38252412 | 2024 | IκB kinase thwarts aggregation: Phosphorylating TDP-43 for degradation. | 0 |
| 38261982 | 2024 | Cognitive and Behavioral Features of Patients With Amyotrophic Lateral Sclerosis Who Are Carriers of the TARDBP Pathogenic Variant. | 0 |
| 38266517 | 2024 | The influence of limbic-predominant age-related TDP-43 encephalopathy on argyrophilic grain disease: A voxel-based morphometry analysis of pathologically confirmed cases. | 0 |
| 38277467 | 2024 | Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. | 20 |
| 38290242 | 2024 | Genetically encoded lysine photocage for spatiotemporal control of TDP-43 nuclear import. | 0 |
Citation
Dessen P
TARDBP (TAR DNA binding protein)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51706/tardbp
