Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51497
MIM: 605297
HGNC: 15934
Ensembl: ENSG00000101158
Variants:
dbSNP: 51497
ClinVar: 51497
TCGA: ENSG00000101158
COSMIC: NELFCD
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101158 | ENST00000460601 | X6RLT1 |
| ENSG00000101158 | ENST00000602795 | H0UI80 |
| ENSG00000101158 | ENST00000652272 | Q8IXH7 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA151249535 | diuretics | Chemical | ClinicalAnnotation | associated | PD | ||
| PA164713347 | Thiazides, plain | Chemical | ClinicalAnnotation | associated | PD | ||
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | ||
| PA449899 | hydrochlorothiazide | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38809918 | 2024 | TH1L involvement in colorectal cancer pathogenesis by regulation of CCL20 through the NF-κB signalling pathway. | 1 |
| 38809918 | 2024 | TH1L involvement in colorectal cancer pathogenesis by regulation of CCL20 through the NF-κB signalling pathway. | 1 |
| 37591184 | 2023 | Structural basis of the human negative elongation factor NELF-B/C/E ternary complex. | 1 |
| 37591184 | 2023 | Structural basis of the human negative elongation factor NELF-B/C/E ternary complex. | 1 |
| 29795304 | 2018 | NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population. | 7 |
| 29795304 | 2018 | NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population. | 7 |
| 27282391 | 2016 | Architecture and RNA binding of the human negative elongation factor. | 38 |
| 27282391 | 2016 | Architecture and RNA binding of the human negative elongation factor. | 38 |
| 22238675 | 2012 | Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration. | 4 |
| 22238675 | 2012 | Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration. | 4 |
| 20028984 | 2010 | Human negative elongation factor activates transcription and regulates alternative transcription initiation. | 31 |
| 20069563 | 2010 | Trihydrophobin 1 attenuates androgen signal transduction through promoting androgen receptor degradation. | 5 |
| 20735431 | 2010 | Negative role of trihydrophobin 1 in breast cancer growth and migration. | 5 |
| 20028984 | 2010 | Human negative elongation factor activates transcription and regulates alternative transcription initiation. | 31 |
| 20069563 | 2010 | Trihydrophobin 1 attenuates androgen signal transduction through promoting androgen receptor degradation. | 5 |
Citation
Dessen P
NELFCD (negative elongation factor complex member C/D)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51720/nelfcd
