Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5000
MIM: 603056
HGNC: 8490
Ensembl: ENSG00000115947
Variants:
dbSNP: 5000
ClinVar: 5000
TCGA: ENSG00000115947
COSMIC: ORC4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29036220 | 2017 | Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast. | 16 |
| 29036220 | 2017 | Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast. | 16 |
| 26124052 | 2015 | HsOrc4-Dependent Dna Remodeling of the ori-β Dhfr Replicator. | 1 |
| 26124052 | 2015 | HsOrc4-Dependent Dna Remodeling of the ori-β Dhfr Replicator. | 1 |
| 22333897 | 2012 | Meier-Gorlin syndrome genotype-phenotype studies: 35 individuals with pre-replication complex gene mutations and 10 without molecular diagnosis. | 56 |
| 22333897 | 2012 | Meier-Gorlin syndrome genotype-phenotype studies: 35 individuals with pre-replication complex gene mutations and 10 without molecular diagnosis. | 56 |
| 21358631 | 2011 | Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome. | 92 |
| 21358631 | 2011 | Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome. | 92 |
| 19690980 | 2010 | Human initiation protein Orc4 prefers triple stranded DNA. | 8 |
| 19690980 | 2010 | Human initiation protein Orc4 prefers triple stranded DNA. | 8 |
| 20010161 | 2009 | Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. | 9 |
| 20010161 | 2009 | Novel ORC4L gene mutation in B-cell lymphoproliferative disorders. | 9 |
| 19074885 | 2008 | Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. | 32 |
| 19074885 | 2008 | Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia. | 32 |
| 15910003 | 2005 | Ku80 binds to human replication origins prior to the assembly of the ORC complex. | 17 |
Citation
Dessen P
ORC4 (origin recognition complex subunit 4)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51730/orc4
