Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84944
MIM: 611368
HGNC: 25929
Ensembl: ENSG00000143194
Variants:
dbSNP: 84944
ClinVar: 84944
TCGA: ENSG00000143194
COSMIC: MAEL
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Gene Silencing by RNA | REACTOME | R-HSA-211000 |
| PIWI-interacting RNA (piRNA) biogenesis | REACTOME | R-HSA-5601884 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38301040 | 2024 | MAEL in human cancers and implications in prognostication and predicting benefit from immunotherapy over VEGFR/mTOR inhibitors in clear cell renal cell carcinoma: a bioinformatic analysis. | 0 |
| 38301040 | 2024 | MAEL in human cancers and implications in prognostication and predicting benefit from immunotherapy over VEGFR/mTOR inhibitors in clear cell renal cell carcinoma: a bioinformatic analysis. | 0 |
| 36779514 | 2023 | The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia. | 0 |
| 36779514 | 2023 | The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia. | 0 |
| 35488386 | 2022 | Identification of MAEL as a promoter for the drug resistance model of iPSCs derived from T-ALL. | 3 |
| 35513870 | 2022 | Maelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer. | 1 |
| 35488386 | 2022 | Identification of MAEL as a promoter for the drug resistance model of iPSCs derived from T-ALL. | 3 |
| 35513870 | 2022 | Maelstrom promotes tumor metastasis through regulation of FGFR4 and epithelial-mesenchymal transition in epithelial ovarian cancer. | 1 |
| 33902648 | 2021 | MAEL as a diagnostic marker for the early detection of esophageal squamous cell carcinoma. | 1 |
| 33902648 | 2021 | MAEL as a diagnostic marker for the early detection of esophageal squamous cell carcinoma. | 1 |
| 30488287 | 2020 | MAEL Cancer-Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with Helicobacter pylori Infection. | 3 |
| 30488287 | 2020 | MAEL Cancer-Testis Antigen as a Diagnostic Marker in Primary Stages of Gastric Cancer with Helicobacter pylori Infection. | 3 |
| 31386627 | 2019 | Long intergenic non-protein coding RNA 511 promotes the progression of osteosarcoma cells through sponging microRNA 618 to upregulate the expression of maelstrom. | 13 |
| 31386627 | 2019 | Long intergenic non-protein coding RNA 511 promotes the progression of osteosarcoma cells through sponging microRNA 618 to upregulate the expression of maelstrom. | 13 |
| 30082413 | 2018 | Maelstrom Directs Myeloid-Derived Suppressor Cells to Promote Esophageal Squamous Cell Carcinoma Progression via Activation of the Akt1/RelA/IL8 Signaling Pathway. | 22 |
Citation
Dessen P
MAEL (maelstrom spermatogenic transposon silencer)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51735/mael
