TIPARP (TCDD inducible poly(ADP-ribose) polymerase)

2010-11-01  

Identity

HGNC
LOCATION
3q25.31
LOCUSID
ALIAS
ARTD14,PARP7,pART14

Other Information

Locus ID:

NCBI: 25976
MIM: 612480
HGNC: 23696
Ensembl: ENSG00000163659

Variants:

dbSNP: 25976
ClinVar: 25976
TCGA: ENSG00000163659
COSMIC: TIPARP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163659ENST00000295924Q7Z3E1
ENSG00000163659ENST00000461166Q7Z3E1
ENSG00000163659ENST00000473702C9JXM5
ENSG00000163659ENST00000481853G5E9W1
ENSG00000163659ENST00000486483Q7Z3E1
ENSG00000163659ENST00000495891H7C5K7
ENSG00000163659ENST00000542783Q7Z3E1

Expression (GTEx)

0
10
20
30
40
50
60

References

Pubmed IDYearTitleCitations
370779372023Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells.5
377680842023Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus.2
380115622023PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis.3
370779372023Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells.5
377680842023Transcriptome screening identifies TIPARP as an antiviral host factor against the Getah virus.2
380115622023PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis.3
365360862022TIPARP is involved in the regulation of intraocular pressure.2
365360862022TIPARP is involved in the regulation of intraocular pressure.2
334750842021Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets.34
334750852021Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells.30
335724752021Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling.12
337998072021PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells.16
339761872021Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly.17
342642862021PARP7 mono-ADP-ribosylates the agonist conformation of the androgen receptor in the nucleus.7
343756122021PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.49

Citation

Dessen P

TIPARP (TCDD inducible poly(ADP-ribose) polymerase)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51750/tiparp