IPO4 (importin 4)

2010-11-01  

Identity

HGNC
LOCATION
14q12
LOCUSID
ALIAS
Imp4
FUSION GENES

Other Information

Locus ID:

NCBI: 79711
HGNC: 19426
Ensembl: ENSG00000196497

Variants:

dbSNP: 79711
ClinVar: 79711
TCGA: ENSG00000196497
COSMIC: IPO4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196497ENST00000354464Q8TEX9
ENSG00000196497ENST00000558046H0YKG5
ENSG00000196497ENST00000558233H0YN07
ENSG00000196497ENST00000558780H0YL92
ENSG00000196497ENST00000559253H0YLV0
ENSG00000196497ENST00000560155H0YN14
ENSG00000196497ENST00000561034H0YK93
ENSG00000196497ENST00000561462H0YMR4
ENSG00000196497ENST00000625289H0YLV0

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
326613232020Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer.12
326613232020Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer.12
308611762019Importin-4 functions as a driving force in human primary gastric cancer.7
308611762019Importin-4 functions as a driving force in human primary gastric cancer.7
282546342017Competitive regulation of IPO4 transcription by ELK1 and GABP.3
282546342017Competitive regulation of IPO4 transcription by ELK1 and GABP.3
275286062016Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.28
275286062016Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.28
208055092010CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.22
208055092010CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.22
197888882009Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.38
197888882009Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.38
162077052005Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor.19
162077052005Importin 4 is responsible for ligand-independent nuclear translocation of vitamin D receptor.19

Citation

Dessen P

IPO4 (importin 4)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51761/ipo4