AKNA (AT-hook transcription factor)

2010-11-01  

Identity

HGNC
AKNA
LOCATION
9q32
LOCUSID
80709
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80709
MIM: 605729
HGNC: 24108
Ensembl: ENSG00000106948

Variants:

dbSNP: 80709
ClinVar: 80709
TCGA: ENSG00000106948
COSMIC: AKNA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106948ENST00000223791Q7Z591
ENSG00000106948ENST00000307564Q7Z591
ENSG00000106948ENST00000312033Q7Z591
ENSG00000106948ENST00000374075Q7Z591
ENSG00000106948ENST00000374079Q7Z591
ENSG00000106948ENST00000374088Q7Z591

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
368356222023Critical Role of the Transcription Factor AKNA in T-Cell Activation: An Integrative Bioinformatics Approach.0
368356222023Critical Role of the Transcription Factor AKNA in T-Cell Activation: An Integrative Bioinformatics Approach.0
346808892021A Homozygous AKNA Frameshift Variant Is Associated with Microcephaly in a Pakistani Family.3
348277072021Functional Role of AKNA: A Scoping Review.3
346808892021A Homozygous AKNA Frameshift Variant Is Associated with Microcephaly in a Pakistani Family.3
348277072021Functional Role of AKNA: A Scoping Review.3
323674042020An exome-first approach to aid in the diagnosis of primary ciliary dyskinesia.11
324605352020Evaluation of Common Variants in the AKNA Gene and Susceptibility to Knee Osteoarthritis Among the Han Chinese.2
324620102020AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways.5
323674042020An exome-first approach to aid in the diagnosis of primary ciliary dyskinesia.11
324605352020Evaluation of Common Variants in the AKNA Gene and Susceptibility to Knee Osteoarthritis Among the Han Chinese.2
324620102020AKNA Is a Potential Prognostic Biomarker in Gastric Cancer and Function as a Tumor Suppressor by Modulating EMT-Related Pathways.5
307874422019The centrosome protein AKNA regulates neurogenesis via microtubule organization.34
307874422019The centrosome protein AKNA regulates neurogenesis via microtubule organization.34
293682742018The association of AKNA gene polymorphisms with knee osteoarthritis suggests the relevance of this immune response regulator in the disease genetic susceptibility.4

Citation

Dessen P

AKNA (AT-hook transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51764/teaching-explorer/css/meetings/