Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 162394
MIM: 614952
HGNC: 28286
Ensembl: ENSG00000166750
Variants:
dbSNP: 162394
ClinVar: 162394
TCGA: ENSG00000166750
COSMIC: SLFN5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166750 | ENST00000299977 | Q08AF3 |
| ENSG00000166750 | ENST00000542451 | B4E128 |
| ENSG00000166750 | ENST00000592325 | Q08AF3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36747204 | 2023 | SLFN5 promotes reversible epithelial and mesenchymal transformation in ovarian cancer. | 0 |
| 36747204 | 2023 | SLFN5 promotes reversible epithelial and mesenchymal transformation in ovarian cancer. | 0 |
| 35687115 | 2022 | Schlafen 5 suppresses human immunodeficiency virus type 1 transcription by commandeering cellular epigenetic machinery. | 7 |
| 35687115 | 2022 | Schlafen 5 suppresses human immunodeficiency virus type 1 transcription by commandeering cellular epigenetic machinery. | 7 |
| 33432153 | 2021 | Comparative proteomics identifies Schlafen 5 (SLFN5) as a herpes simplex virus restriction factor that suppresses viral transcription. | 22 |
| 33985973 | 2021 | SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer. | 18 |
| 33432153 | 2021 | Comparative proteomics identifies Schlafen 5 (SLFN5) as a herpes simplex virus restriction factor that suppresses viral transcription. | 22 |
| 33985973 | 2021 | SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer. | 18 |
| 32488136 | 2020 | Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription. | 16 |
| 32488136 | 2020 | Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription. | 16 |
| 30844429 | 2019 | SLFN5 suppresses cancer cell migration and invasion by inhibiting MT1-MMP expression via AKT/GSK-3β/β-catenin pathway. | 34 |
| 31472120 | 2019 | Overexpression of SLFN5 induced the epithelial-mesenchymal transition in human lung cancer cell line A549 through β-catenin/Snail/E-cadherin pathway. | 8 |
| 30844429 | 2019 | SLFN5 suppresses cancer cell migration and invasion by inhibiting MT1-MMP expression via AKT/GSK-3β/β-catenin pathway. | 34 |
| 31472120 | 2019 | Overexpression of SLFN5 induced the epithelial-mesenchymal transition in human lung cancer cell line A549 through β-catenin/Snail/E-cadherin pathway. | 8 |
| 27032393 | 2017 | SCHLAFEN 5 expression correlates with intestinal metaplasia that progresses to gastric cancer. | 26 |
Citation
Dessen P
SLFN5 (schlafen family member 5)
Atlas Genet Cytogenet Oncol Haematol. 2011-02-01
Online version: http://atlasgeneticsoncology.org/gene/52062/slfn5
