STIP1 (stress induced phosphoprotein 1)

2011-02-01  

Identity

HGNC
LOCATION
11q13.1
LOCUSID
ALIAS
HEL-S-94n,HOP,IEF-SSP-3521,P60,STI1,STI1L
FUSION GENES

Other Information

Locus ID:

NCBI: 10963
MIM: 605063
HGNC: 11387
Ensembl: ENSG00000168439

Variants:

dbSNP: 10963
ClinVar: 10963
TCGA: ENSG00000168439
COSMIC: STIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168439ENST00000305218P31948
ENSG00000168439ENST00000305218V9HW72
ENSG00000168439ENST00000358794P31948
ENSG00000168439ENST00000536973F5GXD8
ENSG00000168439ENST00000538945P31948
ENSG00000168439ENST00000540887H0YGI8
ENSG00000168439ENST00000543847F5H783

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Prion diseasesKEGGko05020
Prion diseasesKEGGhsa05020

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10832corticosteroidsChemicalVariantAnnotationnot associatedPD27523435
PA443450AsthmaDiseaseVariantAnnotationnot associatedPD27523435

References

Pubmed IDYearTitleCitations
384920992024Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.0
384920992024Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.0
374422662023Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.0
378065172023LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein.1
374422662023Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.0
378065172023LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein.1
352695622022JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells.4
352695622022JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells.4
315160812021GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population.5
324002872021Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders.3
334170012021Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia.12
336657862021Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.4
337665392021STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.7
346776452021The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.16
315160812021GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population.5

Citation

Dessen P

STIP1 (stress induced phosphoprotein 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52069/stip1