ASB9 (ankyrin repeat and SOCS box containing 9)

2011-02-01  

Identity

HGNC
LOCATION
Xp22.2
LOCUSID
FUSION GENES

Other Information

Locus ID:

NCBI: 140462
MIM: 300890
HGNC: 17184
Ensembl: ENSG00000102048

Variants:

dbSNP: 140462
ClinVar: 140462
TCGA: ENSG00000102048
COSMIC: ASB9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102048ENST00000380483Q96DX5
ENSG00000102048ENST00000380483A0A024RBZ4
ENSG00000102048ENST00000380485Q96DX5
ENSG00000102048ENST00000380485A0A024RBW2
ENSG00000102048ENST00000380488Q96DX5
ENSG00000102048ENST00000380488A0A024RBW7
ENSG00000102048ENST00000477346R4GN94
ENSG00000102048ENST00000546332Q96DX5
ENSG00000102048ENST00000546332A0A024RBW2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366831112023Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation.3
366831112023Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation.3
325139592020Structure and dynamics of the ASB9 CUL-RING E3 Ligase.15
325139592020Structure and dynamics of the ASB9 CUL-RING E3 Ligase.15
273968302016Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer.7
273968302016Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer.7
256542632015How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase.9
256542632015How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase.9
238375922013Multimeric complexes among ankyrin-repeat and SOCS-box protein 9 (ASB9), ElonginBC, and Cullin 5: insights into the structure and assembly of ECS-type Cullin-RING E3 ubiquitin ligases.15
238375922013Multimeric complexes among ankyrin-repeat and SOCS-box protein 9 (ASB9), ElonginBC, and Cullin 5: insights into the structure and assembly of ECS-type Cullin-RING E3 ubiquitin ligases.15
224188392012Crystal structure of Human ASB9-2 and substrate-recognition of CKB.8
224188392012Crystal structure of Human ASB9-2 and substrate-recognition of CKB.8
203026262010ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function.30
208780582010Clinical significance of ASB9 in human colorectal cancer.16
203026262010ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function.30

Citation

Dessen P

ASB9 (ankyrin repeat and SOCS box containing 9)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52072/asb9