GPR55 (G protein-coupled receptor 55)

2011-03-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
LPIR1

Other Information

Locus ID:

NCBI: 9290
MIM: 604107
HGNC: 4511
Ensembl: ENSG00000135898

Variants:

dbSNP: 9290
ClinVar: 9290
TCGA: ENSG00000135898
COSMIC: GPR55

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135898ENST00000392039Q9Y2T6
ENSG00000135898ENST00000392039A8K858
ENSG00000135898ENST00000392040Q9Y2T6
ENSG00000135898ENST00000392040A8K858
ENSG00000135898ENST00000438398C9J1P7
ENSG00000135898ENST00000444078Q9Y2T6
ENSG00000135898ENST00000444078A8K858
ENSG00000135898ENST00000622008Q9Y2T6
ENSG00000135898ENST00000622008A8K858
ENSG00000135898ENST00000650999Q9Y2T6
ENSG00000135898ENST00000650999A8K858

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
375449352023Lysophosphatidylglucoside/GPR55 signaling promotes foam cell formation in human M2c macrophages.2
376887692023A comprehensive survival and prognosis analysis of GPR55 expression in hepatocellular carcinoma.1
378668082023Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: Prenatal lysophosphatidylinositol attenuates valproic acid-induced synaptic abnormalities and mitochondrial dysfunction.1
379983802023Elucidation of GPR55-Associated Signaling behind THC and LPI Reducing Effects on Ki67-Immunoreactive Nuclei in Patient-Derived Glioblastoma Cells.0
375449352023Lysophosphatidylglucoside/GPR55 signaling promotes foam cell formation in human M2c macrophages.2
376887692023A comprehensive survival and prognosis analysis of GPR55 expression in hepatocellular carcinoma.1
378668082023Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: Prenatal lysophosphatidylinositol attenuates valproic acid-induced synaptic abnormalities and mitochondrial dysfunction.1
379983802023Elucidation of GPR55-Associated Signaling behind THC and LPI Reducing Effects on Ki67-Immunoreactive Nuclei in Patient-Derived Glioblastoma Cells.0
355629472022Prognostic Significance of GPR55 mRNA Expression in Colon Cancer.4
355629472022Prognostic Significance of GPR55 mRNA Expression in Colon Cancer.4
323290852021The L-α-Lysophosphatidylinositol/G Protein-Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis.28
339025962021Peptide targeting of lysophosphatidylinositol-sensing GPR55 for osteoclastogenesis tuning.4
339524592021Expression of Lysophosphatidylinositol Signaling-relevant Molecules in Colorectal Cancer.3
339599682021BRET analysis reveals interaction between the lysophosphatidic acid receptor LPA2 and the lysophosphatidylinositol receptor GPR55 in live cells.2
342374322021Lysophosphatidylglucoside is a GPR55 -mediated chemotactic molecule for human monocytes and macrophages.2

Citation

Dessen P

GPR55 (G protein-coupled receptor 55)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52097/gpr55