Identity
HGNC
LOCATION
1q32.2
LOCUSID
ALIAS
LPS,OFC6,PIT,PPS,PPS1,VWS,VWS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3664
MIM: 607199
HGNC: 6121
Ensembl: ENSG00000117595
Variants:
dbSNP: 3664
ClinVar: 3664
TCGA: ENSG00000117595
COSMIC: IRF6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166119041 | drug-induced liver injury | Disease | ClinicalAnnotation | associated | PD | 30013178 | |
| PA444987 | Multiple Sclerosis | Disease | ClinicalAnnotation | associated | PD | 30013178 | |
| PA450037 | interferon beta-1a | Chemical | ClinicalAnnotation | associated | PD | 30013178 | |
| PA450039 | interferon beta-1b | Chemical | ClinicalAnnotation | associated | PD | 30013178 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36866619 | 2024 | Causal Variations at IRF6 Gene Identified in Van der Woude Syndrome Pedigrees. | 1 |
| 38311552 | 2024 | [Correlation between methylation of interferon regulatory factor 6 gene promoter in renal tissues and overall survival of patients with Kidney renal clear cell carcinoma]. | 0 |
| 38429584 | 2024 | Biophysical and functional characterization of N-terminal domain of Human Interferon Regulatory Factor 6. | 0 |
| 38493179 | 2024 | Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value. | 2 |
| 38546517 | 2024 | Review on the Role of IRF6 in the Pathogenesis of Non-syndromic Orofacial Clefts. | 0 |
| 38809584 | 2024 | A novel noncanonical function for IRF6 in the recycling of E-cadherin. | 0 |
| 36866619 | 2024 | Causal Variations at IRF6 Gene Identified in Van der Woude Syndrome Pedigrees. | 1 |
| 38311552 | 2024 | [Correlation between methylation of interferon regulatory factor 6 gene promoter in renal tissues and overall survival of patients with Kidney renal clear cell carcinoma]. | 0 |
| 38429584 | 2024 | Biophysical and functional characterization of N-terminal domain of Human Interferon Regulatory Factor 6. | 0 |
| 38493179 | 2024 | Identification and validation of IRF6 related to ovarian cancer and biological function and prognostic value. | 2 |
| 38546517 | 2024 | Review on the Role of IRF6 in the Pathogenesis of Non-syndromic Orofacial Clefts. | 0 |
| 38809584 | 2024 | A novel noncanonical function for IRF6 in the recycling of E-cadherin. | 0 |
| 34894020 | 2023 | Association between variants around IRF6 and non-syndromic orofacial cleft in Western Han Chinese. | 1 |
| 36484949 | 2023 | Association of single nucleotide polymorphisms in the IRF6 gene with nonsyndromic cleft lip with or without cleft palate in Kinh Vietnamese patients. | 0 |
| 36847740 | 2023 | The IRF6 AP-2α binding site polymorphism relate to the severity of non-syndromic orofacial cleft of Indonesian patients. | 0 |
Citation
Dessen P
IRF6 (interferon regulatory factor 6)
Atlas Genet Cytogenet Oncol Haematol. 2011-03-01
Online version: http://atlasgeneticsoncology.org/gene/52118/irf6
